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  1. CORESTA Congress, Online, 2022, Smoke Science/Product Technology Groups, ST 19

    Interaction mechanisms between S/R-nicotine and human serum albumin

    YANG Ji; LIU Chunbo; ZHU Ruizhi; YIN Zhijiang; LIU Ze; TIAN Ran; TANG Shiyun; XIA Jianjun; SI Xiaoxi;JIANG Wei; LI Zhengjie; LIU Zhihua
    Technology Center of China Tobacco Yunnan Industrial Co., Ltd., Kunming, China
    Nicotine is an asymmetric molecule with two enantiomers, namely S-nicotine and R-nicotine.  Studies have shown that different configurations of nicotine have different physiological activities in the body.  Therefore, taking human serum...
  2. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, STPOST 13

    Analysis of menthol optical isomers in tobacco products

    SI Xiaoxi; ZHU Ruizhi; TANG Jianguo; MIAO Mingming; LIU Zhihua
    Yunnan Key Laboratory of Tobacco Chemistry, R&D Center of China Tobacco Yunnan Industrial Co., Ltd. of CNTC, No. 367, Hongjin Road, Kunming 650231, Yunnan, P.R. China
    Menthol can exist in four enantiomeric pairs, each of which has D-type and L-type separately. Different menthol isomers possess different sensory properties. The establishment of configuration analysis technology for the menthol isomer is of great...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 42

    Study on aerosol deposition in the respiratory tract of consumers using cigarette, electronic cigarette or heat-not-burn product

    CUI Huapeng(1); LI Yawen(1); FAN Meijuan(1); CHEN Li(1); SI Xiaoxi(2); HAN Jingmei(2); CAI Junlan(1); LI Xiang(1); LIU Shaofeng(1); XIE Fuwei(1); XIE Jianping(1)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China; (2) R&D Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China
    The deposition of aerosols inhaled into the human respiratory tract is key to evaluate exposure and risk during product use. A method based on a differential mobility spectrometer (DMS) was established for determining the physical properties of...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 67

    Study on combustibility and particle size distribution in smoke aerosols of cigarettes with different circumferences

    ZHU Ruizhi; SI Xiaoxi; LI Zhenjie; HE Pei; WANG Kai; YOU Junheng; JIANG Wei; SHEN Qinpeng; SU Zhongbi; LIU Zhihua
    R&D Center of China Tobacco Yunnan Industrial Co. Ltd of CNTC, Yunnan, P.R. China
    In order to investigate the effects of cigarette circumference on its combustibility and particle size distribution in smoke aerosol, the solid phase temperature of combustion cone and the gas phase temperature in filter tip of the same brand...
  5. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 28

    Determination of benzo[a]pyrene in smokers’ urine by online gel permeation chromatography–solid phase extraction–gas chromatography/mass spectrometry

    SI Xiaoxi; ZHU Ruizhi; LIU Zhihua; ZHANG Fengmei; LIU Chunbo; SHEN Qinpeng; HE Pei; MIAO Mingming; YANG Guangyu
    Key Laboratory of Tobacco Chemistry of Yunnan, R&D Center of China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China
    A new method for determining the benzo[a]pyrene (B[a]P) in samples of smokers’ urine was developed with an online gel permeation chromatography-solid phase extraction-gas chromatography/mass spectrometry (GPC-SPE-GC/MS) hyphenated system. Urine...