CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 38
In vitro to in vivo extrapolation (IVIVE) for evaluating exposure and health impacts of e-vapor products using ingredient and mixture in vitro data
(1) Altria Client Services LLC, Richmond, VA, U.S.A.; (2) Integrated Laboratory Systems (ILS), RTP, NC, U.S.A.
In Vitro to In Vivo Extrapolation (IVIVE) uses reverse dosimetry to translate in vitro bioactivity data to clinically relevant exposure metrics. This study applies the IVIVE approach to e-vapor products using reported in vitro cytotoxicity data of...