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  1. CORESTA Congress, Online, 2022, Smoke Science/Product Technology Groups, ST 70

    Evaluation on accuracy improvement of GC-MS determination of seven minor alkaloids in mainstream cigarette smoke by novel analyte protectants

    WANG Xiaoyu(1); GUO Qiong(1); Li Xianyi(2); QIN Yaqiong(1); Mao Deshou(2); PAN Lining(1); XIE Fuwei(1); LIU Shaofeng(1); Liao Tougen(2); LIU Huimin(1)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, China; (2) R&D Center, China Tobacco Yunnan Industrial Co., Kunming, China
    Tobacco minor alkaloids are important precursor substances of TSNAs. Therefore, their accurate quantifications are of great significance. In order to realise determinations of seven minor alkaloids in mainstream cigarette smoke with high accuracy and...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 36

    Simultaneous detection of 35 organosulfur compounds in cigarette smoke by GC-MS/MS coupled with sulfur chemiluminescence detector

    QIN Yaqiong; LIU Ruihong; WANG Xiaoyu; XIE Fuwei; PAN Lining; CHEN Li; WANG Bing; YU Jingjing; CAI Junlan; LIU Shaofeng
    Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, China
    Organosulfur compounds are of great concern in food science because they play an important role in the flavour and taste of food due to their extremely low odour threshold levels and high sensory impact. They also exist in cigarette smoke, mainly in...
  3. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 72

    Study on nicotine exposure level of electronic cigarette smokers

    HUA Chenfeng; WANG Sheng; ZHAO Ge; LIU Kejian; QIAO Liangjun; ZHAO Junwei; PAN Lining; SHANG Pingping; LI Xiang; XIE Fuwei
    Zhengzhou Tobacco Research Institute of CNTC, No. 2 Fengyang Street, High-Tech Zone, Zhengzhou, China
    Different opinions have been generated on e-cigarettes in helping to quit smoking and causing nicotine dependence. In order to better understand the nicotine exposure levels of e-cigarette only smokers (ES), this study used the HPLC-MS/MS method to...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 42

    Study on aerosol deposition in the respiratory tract of consumers using cigarette, electronic cigarette or heat-not-burn product

    CUI Huapeng(1); LI Yawen(1); FAN Meijuan(1); CHEN Li(1); SI Xiaoxi(2); HAN Jingmei(2); CAI Junlan(1); LI Xiang(1); LIU Shaofeng(1); XIE Fuwei(1); XIE Jianping(1)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China; (2) R&D Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China
    The deposition of aerosols inhaled into the human respiratory tract is key to evaluate exposure and risk during product use. A method based on a differential mobility spectrometer (DMS) was established for determining the physical properties of...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 48

    Analysis of four volatile nitroso-amines, four alkaloids, 18 polycyclic aromatic hydrocarbons in oral tobacco products based on simultaneous extraction technique and GC-MS/MS detection

    WANG Xiaoyu(1); QIN Yaqiong(1); XIE Fuwei(1); LI Dongliang(2); SHEN Yi(2); GUO Junwei(1); LIU Shaofeng(1); LUO Cheng(2); PAN Lining(1); WANG Sheng(1)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China; (2) Technology Center, China Tobacco Sichuan Industrial Co., Ltd., Chengdu, P.R. China
    Many kinds of harmful or potentially harmful components (HPHCs) exist in oral tobacco products. Usually, each kind of chemical needs a specific analytical method, which will cause high cost and low throughput. Therefore, the objective of this study...
  6. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups (Workshop), STW 02

    Quantitative risk assessment (QRA)-based prioritization of mainstream cigarette smoke toxicants

    LI Xiang(1); SHANG Pingping(1); XIE Fuwei(1); ZHU Maoxiang(2); YANG Zhihua(2);NIE Cong(1); LIU Huimin(1); XIE Jianping(1)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China; (2) Beijing Institute of Radiation Medicine, Beijing, P.R. China
    In 2008, seven representative toxicants in mainstream cigarette smoke were screened and validated by China Tobacco to indicate the harmfulness of mainstream cigarette smoke, which included carbon monoxide (CO), hydrogen cyanide (HCN),...
  7. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 44

    Time and spatially resolved in-situ determination of temperature, pressure and gas phase concentration of selected smoke constituents inside a burning superslim cigarette. Part I – Thermophysical mapping

    CUI Huapeng(1); EHLERT S.(2); XIE Fuwei(1); DENG Nan(1); LI Bin(1); LIU Chuan(3); McADAM K.(3); WALTE A.(2); ZIMMERMANN R.(2)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China; (2) Photonion GmbH, Schwerin, Germany; (3) British American Tobacco (Investments) Limited, Global R&D, Southampton, U.K.
    Superslim cigarettes in China are a relevant product category on the market. Accurate determination of key thermo-physical and -chemical parameters in superslim cigarettes are essential for the mechanistic understanding of combustion as well as...
  8. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 45

    Time and spatially resolved in-situ temperature and pressure measurements with soft ionisation mass spectrometry inside a burning superslim cigarette. Part II – thermochemical mapping

    EHLERT S.(1,3); CUI Huapeng.(2); HEIDE J.(3); XIE Fuwei(2); DENG Nan(2); LIU Chuan(4); McADAM K.(4); WALTE A.(1); ZIMMERMANN R.(3)
    (1) Photonion GmbH, Schwerin, Germany; (2) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China; (3) University of Rostock, Dept. of Analytical Chemistry, Rostock, Germany; (4) British American Tobacco, R&D Centre, Southampton, U.K.
    Superslim cigarettes are an increasingly popular category of cigarettes in China. Accurate measurements of key thermophysical and thermochemical parameters in superslim cigarettes is essential for mechanistic understanding of pyrolysis processes,...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 13

    The comparative assessment of e-cigarettes and cigarettes on cytotoxicity and proinflammatory cytokine secretion level using an air-liquid interface system

    HUA Chenfeng; QIAO Liangjun; KANG Yu; ZHAO Junwei; QIN Yaqiong; CUI Huapeng; SHANG Pingping; LIU Huimin; LI Xiang; XIE Fuwei
    Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China
    Electronic cigarettes (e-cigarettes), as an alternative to combustible cigarettes, have become more and more popular. In this study, the cytotoxic and proinflammatory cytokine secretion response of e-cigarette vapour (e-vapour) and traditional...
  10. TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 098

    Oxidative stress and oxidative damage in human lung epithelial cells induced by total particulate matter extractions from three different tobaccos

    KANG Yu; QIAO Liangiun; HU Qiao; HUA Chenfeng; XIE Fuwei; SHANG Pingping; LI Xiang; ZHAO Junwei
    Zhengzhou Tobacco Research Institute, Zhengzhou, China
    Global sales and popularity of e-cigarettes have been growing rapidly in the past few years, but there is still a big share of conventional cigarettes and other tobacco products, which had led to the concerns about the toxicities of different tobacco...