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64 results

  1. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 41

    Comparison of collection strategies for the analysis of targeted compounds in e-cigarettes aerosol

    JAMESON J.B.; HIRAKI B.J.; OZVALD A.M.; JEONG L.N.; CHEN X.; GILLMAN I.G.
    JUUL Labs Inc., 1000 F Street NW, Washington, DC 20004, USA
    The Premarket Tobacco Product Application (PMTA) process for ENDS recommends that a wide range of Harmful and Potentially Harmful Compounds (HPHCs) be determined to support the application. The U.S. Food and Drug Administration provides guidance...
  2. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 43

    Evidence for artefactual formation of glycidol during the analysis of e-liquids

    GILLMAN I.G.; O’REGAN D.C.; OZVALD A.M.; COOK D.K.; JEONG LENA; CHEN XIN
    JUUL Labs Inc., 1000 F Street NW, Washington, DC 20004, USA
    The Premarket Tobacco Product Application (PMTA) process for ENDS recommends that a wide range of Harmful and Potentially Harmful Compounds (HPHCs) be determined to support the application. The U.S. Food and Drug Administration (FDA) provides...
  3. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 45

    Compound identification process for GC-MS non-targeted analysis of JUUL aerosol using a custom mass spectral library

    JEONG L.N.(1); NOE M.R.(2); SHAH N.H.(2); CHAKRABORTY S.(2); MILLER IV J.H.(2); GILLMAN I.G.(1)
    (1) JUUL Labs, Inc., 1000 F Street NW, Washington, DC 20004, USA; (2) Altria Client Services LLC (a Service Provider to Juul Labs, Inc.), 601 East Jackson St, Richmond, VA 23219, USA
    The FDA’s Premarket Tobacco Product Application (PMTA) guidance for Electronic Nicotine Delivery Systems (ENDS) recommends that applicants evaluate unique constituents in the aerosol of ENDS products for potential health risks. There is a need for...
  4. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 50

    Comparison of quartz filter collection and electrostatic precipitation for analysis of trace metals in ENDS aerosol

    JAMESON J.B.; YANG C.; COOK D.K.; JEONG L.N.; GILLMAN I.G.
    JUUL Labs Inc., 1000 F Street NW, Washington, DC 20004, USA
    The Premarket Tobacco Product Application (PMTA) process for ENDS recommends that a wide range of Harmful and Potentially Harmful Compounds (HPHCs) be determined to support the application. The U.S. Food and Drug Administration provides guidance...
  5. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 55

    Targeted characterization of the chemical composition of novel JUUL product aerosol and comparison with 3R4F reference cigarette smoke

    COOK D.K.; O’REGAN D.C.; OZVALD A.O, YANG C.; GILLMAN I.G.
    JUUL Labs Inc., 1000 F Street NW, Washington, DC 20004, USA
    Electronic nicotine delivery systems (ENDS) generally emit reduced levels of harmful and potentially harmful constituents (HPHCs) compared to combustible cigarettes; the degree of constituent reduction can vary across ENDS product designs. In this...
  6. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 08

    Development and validation of a routine method for the determination of carbonyl compounds in heated tobacco products (HTPs) by UPLC-MS

    JABLONSKI J.J.; MARTIN A.M.; GILLMAN I.G.
    Enthalpy Analytical, LLC, Richmond, VA, U.S.A.
    Mainstream smoke is a complex mixture containing > 4800 compounds. Within this mixture there are various carbonyls which are also present on the FDA’s abbreviated and extended harmful and potentially harmful constituents (HPHC) list, such as...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 31 (also presented at TSRC 2019)

    Impact of device variability on the determination of aldehyde compounds in e-cigarette emissions

    GILLMAN I.G.; PENNINGTON A.S.C.; HUMPHRIES K.E.
    Enthalpy Analytical, LLC, Durham NC, U.S.A.
    The determination of aldehyde compounds (formaldehyde, acetaldehyde and acrolein) in e-cigarette emissions has been widely reported in scientific literature. Recent reports have focused on the contribution of flavor compounds in e-liquids and on the...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 07 (also presented at TSRC 2019)

    HPHC analysis of seven flavors of a temperature-regulated nicotine salt-based pod system

    COOK D.(1); HIRAKI B.(1); MISRA M.(1); GILLMAN I.G.(2)
    (1) JUUL Labs, San Francisco, CA, U.S.A.; (2) Enthalpy Analytical, LLC, Richmond, VA, U.S.A.
    The JUUL Nicotine Salt Pod System (NSPS) has no user modifiable settings and is temperature regulated to minimize the generation of combustion related byproducts. Aerosol generated from NSPS pods using a cotton wicking material was evaluated for...