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212 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 02

    Descriptive consumer reported outcome measures and definitions in tobacco and nicotine research: a consensus approach

    WEI L.(1) on behalf of the CROM Task Force: CLERC E.(2); SHETTY M.(3); CHREA C.(2); PRASAD K.(3); SARKAR M.(1)
    (1) Altria Client Services LLC, Richmond, Virginia, U.S.A.; (2) Philip Morris International, Neuchâtel, Switzerland; (3) British American Tobacco, Southampton, U.K.
    The Consumer Reported Outcome Measures (CROM) Consortium Task Force (TF), consisting of academic researchers and members from various tobacco companies, was formed within the Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA) in...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 03

    Psychometric validation of new scales expanding conceptual coverage of the ABOUT-Perceived Risk: perceived social risk and perceived practical risk

    CLERC E.(1); SALZBERGER T.(2); CANO S.(3); AFOLALU E.(1); CHREA C.(1)
    (1) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (2) Institute for Statistics and Mathematics, University of Economics and Business, Vienna, Austria; (3) Modus Outcomes, Letchworth Garden City, U.K.
    The ABOUT™—Perceived Risk is a self-report instrument, developed by Philip Morris Products SA, designed to assess perceived risks associated with the use of a wide range of tobacco and/or nicotine containing products (TNP), such as cigarettes,...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 06 (also presented as poster at TSRC 2021)

    A statistical methodology integrating resampling techniques to evaluate public health impact after introduction of reduced-risks products in Japan

    LARROQUE S.; KUBOTA T.; CHARRIÈRE M.; SONNERAT D.; KIMURA Y.
    JT International SA, 8 Rue Kazem Radjavi, 1202 Geneva, Switzerland; Japan Tobacco Inc., Tokyo, Japan
    Statistical modelling methodologies to predict the impact of reduced-risk products (with the potential to reduce the public health risks associated with smoking, “RRP”), namely e-cigarettes and heated tobacco products, require many input parameters;...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 07

    Nicotine pharmacokinetics of electronic cigarettes: an updated analysis of pooled data from the literature

    JACOBSON K.; MARTINEZ J.; LARROQUE S.; JONES I.; PASCHKE T.
    JT International SA, Geneva, Switzerland
    Several regulatory initiatives around the world restrict the content of nicotine in electronic cigarette (e-cigarette) liquids (e-liquids) in order to minimize the risks associated with nicotine. However, to which extent levels of nicotine in...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 42

    Method development of an in vitro waterpipe air-liquid interface exposure system

    GAFNER J.(1); MILLER-HOLT J.(1); FUKUSHIMA T.(2)
    (1) Scientific and Regulatory Affairs, JT International SA, Geneva, Switzerland; (2) Scientific Product Assessment Center, R&D Group, Japan Tobacco Inc., Kanagawa, Japan
    Waterpipe tobacco smoke (WTS) bubbles through water before being inhaled and is a complex mixture of particulate gases formed by the heating of tobacco, flavourings and humectants, usually using an external charcoal piece. To date, there are no...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 45

    Meta-analysis study to establish population level estimates of NNAL in smokers and non-smokers

    AYALA-FIERRO F.(1); VERRON T.(2); LIZHNYAK P.(3); FREELAND R.(4); FROST-PINEDA K.(4); ELAMIN A.(5); PRASAD G.L.(4); SARKAR M.(3)
    (1) Juul Labs, Inc, U.S.A.; (2) Imperial Brands, U.K.; (3) Altria Client Services, U.S.A.; (4) RAI Services Company, U.S.A.; (5) Philips Morris International, Switzerland
    The purpose of this research (a project of the CORESTA Biomarkers Sub-Group) was to establish a population level estimate for the biomarker of cigarette smoke exposure, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), to serve as a baseline...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 51

    In vitro evaluation of tobacco free nicotine pouches

    MILLER-HOLT J.(1); ABRAHAM I.(1); SAKIMURA M.(1); FUKUSHIMA T.(2); GAFNER J.(1)
    (1) Scientific and Regulatory Affairs, JT International SA, Geneva, Switzerland; (2) Scientific Product Assessment Center, R&D Group, Japan Tobacco Inc., Kanagawa, Japan
    Non-clinical in vitro studies were conducted to investigate the characteristics of tobacco free nicotine pouches alongside a reference snus product and marketed snus product. The investigation included the evaluation of nicotine transfer to...
  8. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 26 (also presented as presentation at CORESTA SSPT2021)

    A statistical methodology integrating resampling techniques to evaluate public health impact after introduction of reduced-risks products in Japan

    LARROQUE S.(1); KUBOTA T.(2); KIMURA Y.(2); CHARRIÈRE M.(1); SONNERAT D.(1)
    (1) JTI Geneva, Geneva Switzerland; (2) Japan Tobacco Inc., Tokyo, Japan
    Statistical modeling methodologies to predict the impact of reduced-risk products (with the potential to reduce the public health risks associated with smoking, “RRP”), namely e-cigarettes and heated tobacco products, require many input parameters;...
  9. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 32

    Development of recommendations of descriptive consumer-reported outcome measures (descriptive-CROM) and related definitions in tobacco and nicotine research

    WEI L.(1) on behalf of CORESTA CROM Task Force: CLERC E.(2); SHETTY M.(3); CHREA C.(2); PRASAD K.(3); SARKAR M.(1)
    (1) Altria Client Services LLC, Richmond, VA, USA; (2) Philip Morris International, Neuchâtel, Switzerland; (3) British American Tobacco, Southampton, UK
    Background: The Consumer Reported Outcome Measures (CROM) Consortium Task Force (TF), consisting of academic researchers and members from various tobacco companies, was formed within the Cooperation Centre for Scientific Research Relative to Tobacco...