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  1. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 06

    Validation of extraction method for tobacco-free nicotine pouches and Swedish snus pouch products - towards standardization of in vitro testing

    TALIKKA M.; GORALCZYK A.; DOS SANTOS D.; ALRIQUET M.; ZANETTI F.; ORTEGA TORRES L.; PAK C.; BERTHOUZOZ M.
    PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland
    Tobacco-free nicotine pouches (NP) and tobacco-containing Swedish snus pouches (Swedish snus) are two types of nicotine-delivery products for oral use. A standard method to generate an extract of these products for in vitro testing has not been...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 16

    Biomarkers assessment in healthy adult smokers who switched from conventional cigarettes to two types of non-combustible tobacco products: a randomized, controlled study

    YUKI D.*; GILES L.; HARBO S.; HEMSLEY A.
    JT International SA, Scientific & Regulatory Affairs, Geneva, Switzerland (* Now at Japan Tobacco Inc., Scientific & Regulatory Affairs, Tokyo, Japan)
    There has been a growing interest in the non-combustible tobacco products, including e-cigarettes and heated tobacco products. Reductions in biomarkers of exposure associated with selected harmful and potentially harmful constituents (HPHCs) have...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 17

    Biomarkers assessment in healthy adult smokers who switched from conventional cigarettes to closed tank e-cigarette: a randomized, controlled study

    YUKI D.*; GILES L.; HARBO S.; HEMSLEY A.
    JT International SA, Scientific & Regulatory Affairs, Geneva, Switzerland (* Now at Japan Tobacco Inc., Scientific & Regulatory Affairs, Tokyo, Japan)
    There has been a growing interest on the non-combustible tobacco products, including e-cigarettes and heated tobacco products. Reductions in biomarkers of exposure associated with selected harmful and potentially harmful constituents (HPHCs) have...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 25

    Nicotine pharmacokinetics and subjective effects of novel heated tobacco product compared to cigarettes: a randomised, crossover study

    YUKI D.*; GILES L.; HARBO S.; HEMSLEY A.
    JT International SA, Scientific & Regulatory Affairs, Geneva, Switzerland (* Now at Japan Tobacco Inc., Scientific & Regulatory Affairs, Tokyo, Japan)
    The nicotine pharmacokinetics (PK) and subjective effects of non-combustible tobacco products, including heated tobacco products, have been widely assessed, with a lower or similar nicotine exposure noted for many products when compared to...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 30

    Comparison of material surface staining following exposure to heated tobacco and e-vapour aerosols versus cigarette smoke

    GOMEZ LUESO M.; RODRIGUES CRESPO K.; GLABASNIA A.; GOUJON-GINGLINGER C.; KLEINHANS S.; MITOVA M.I.; LANG G.
    PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland
    Cigarette smoke deposition on indoor surfaces leads to discoloration, particularly for light-coloured materials. The less complex aerosols emitted by heated tobacco products (HTPs) and e-vapor products (EVPs) contain ≥ 90 % water and...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 46

    Measuring tobacco product experience: CROM adapted from the mCEQ for the assessment of new tobacco products

    MAINY N.(1); BAJEC M.(2); ALVES FAVARO M.(3); SALZBERGER T.(4); ROSE J.(5)
    (1) JT International SA, Geneva, Switzerland; (2) Bajec Senseworks Consulting, Hamilton, Ontario, Canada; (3) Mapi Research Trust, Lyon, France; (4) Institute for Statistics and Mathematics, Institute for Marketing Management, University of Economics and Business (WU Wien), Vienna, Austria; (5) Rose Research Center, Raleigh, NC, U.S.A.
    Originally referred to as the Smoking Effects Inventory (SEI), the self-reported measurement instrument commonly known as the modified Cigarette Evaluation Questionnaire (mCEQ) assesses the reinforcing effects of smoking cigarettes. Like other legacy...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 47

    Systematic review of the design and conduct of actual use studies of new tobacco products

    MAINY N.(1); BAJEC M.(2); RICHARDSON C.(3); RUSSELL C.(4)
    (1) JT International SA, Geneva, Switzerland; (2) Bajec Senseworks Consulting, Hamilton, Ontario, Canada; (3) PEGUS Research, Inc., Salt Lake City, UT, U.S.A.; (4) Russell Burnett Research & Consultancy Ltd, Glasgow, U.K.
    Submission of a Premarket Tobacco Product Application (PMTA) is required for manufacturers seeking a Marketing Granted Order (MGO) from the US Food & Drug Administration (FDA) Center for Tobacco Products (CTP). PMTA assessment of the public...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 50

    Data gap analysis and proposal for environmental chemical risk assessment of cigarette butts

    DOMÍNGUEZ ESTÉVEZ M.; SAYERS K.; PRICE L.; GILES L.
    JT International SA, Geneva, Switzerland
    The environmental impact of cigarette butts (CB) is a public concern with increasing scientific and media attention. Limited studies on the potential ecological risk have led to policy proposals for banning cigarette filters or classifying them as a...
  9. TSRC, Tob. Sci. Res. Conf., 2023, 76, abstr. 105

    Asynchronous online focus groups: qualitative research on reduced-risk nicotine products with underserved or hard-to-reach populations

    SHERWOOD N.(1); OLSON C.K.(2)
    (1) Neil Sherwood Consulting, Nyon, Vaud, Switzerland; (2) McKinney Regulatory Science Advisors, San Carlos, CA USA
    Objectives: New technologies provide alternatives to traditional in-person focus groups for Tobacco Product Perception and Intention (TPPI) studies, allowing inclusion of a diverse range of population subgroups and reducing logistical challenges. We...