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668 results

  1. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 15

    A retrospective analysis of cigarette smoking and ENDS use in a convenience sample of adult users of blu and myblu ENDS

    SELTZER R.G.N.(1); FEARON I.M.(2); HOUSER T.L.(1); NIDES M.(1); TOPE A.(3); CAHOURS X.(3)
    (1) LA Clinical Trials, Burbank, CA, USA; (2) whatIF? Consulting, Harwell, UK; (3) Imperial Brands, Bristol, UK
    Encouraging adult smokers to transition to potentially less harmful nicotine products, like electronic nicotine delivery systems (ENDS), may positively impact individual and population health. However, there is concern that ENDS use by never smokers...
  2. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 20

    Nrf2 response to whole smoke and aerosol of two different tobacco product types in a 3D human airway model

    KEYSER B.M.(1); LEVERETTE R.(1); HOLLINGS M.(2); ROTHWELL E.(2); WERTMAN J.(1); MORGAN(1); FIELDS W.(1)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) Labcorp Early Development Laboratories, Harrogate, North Yorkshire, UK
    The nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway, activated in human lung cells by cigarette smoke, regulates genes involved in the antioxidative stress response. Here, we evaluated the effect of cigarette whole smoke (3R4F...
  3. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 24

    In-vitro toxicity testing of RELX Infinity tobacco and menthol flavored ENDS products compared to reference 1R6F cigarette

    LIU C.(1); MINET E.F.(2); GRAFF D.W.(1)
    (1) RELX International, Shenzhen, Guangdong, China; (2) Broughton Nicotine Services, Earby, Lancashire, UK
    In the Electronic Nicotine Delivery System (ENDS) Premarket Tobacco Product Application guidance, the FDA recommends a weight of evidence approach to demonstrate that ENDS products are appropriate for the protection of public health, including...
  4. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 28

    Premarket assessment of conditional risk perceptions and intentions to use the RELX Infinity ENDS among national probability samples of adult tobacco users and non-users in the United States

    RUSSELL C.; BURNETT R.
    Research and Consultancy, Glasgow, Scotland UK
    Collecting data on tobacco product risk perceptions and use intentions can inform the U.S. Food and Drug Administration’s (FDA) evaluation of the population’s likelihood of using a new tobacco product. This study assessed conditional long term health...
  5. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 29

    Curiosity and intentions to use myblu e-cigarettes and an examination of the gateway theory: data from cross-sectional nationally representative surveys

    FEARON I.M.(1); SELTZER R.G.N.(2); HOUSER T.L.(2); NIDES M.(2); TOPE A.(3); CAHOURS X.(3)
    (1) whatIF? Consulting Ltd, Harwell, UK; (2) LA Clinical Trials, Burbank, CA, USA (3) Imperial Brands, Bristol, UK
    Encouraging adult smokers to transition to potentially less harmful alternative nicotine products, such as electronic nicotine delivery systems (ENDS), may positively impact both individual and population health. However, there is concern that ENDS...
  6. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 30

    Examination of the impact of e-liquid nicotine strength on perceived dependence on myblu ENDS

    FEARON I.M.(1); SELTZER R.G.N.(2); HOUSER T.L.(2); NIDES M.(2); TOPE A.(3); CAHOURS X.(3); VERRON T.(3)
    (1) whatIF? Consulting Ltd, Harwell, UK; (2) LA Clinical Trials, Burbank, CA, USA (3) Imperial Brands, Bristol, UK
    Electronic nicotine delivery systems (ENDS) are a potentially less harmful alternative to combustible cigarette smoking for adult smokers. While it has been proposed that ENDS that have nicotine delivery characteristics similar to that of combustible...
  7. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 31

    Are all e-cigarettes borne equal or are some devices better than others in assisting smokers’ quit attempts? The U.K. U.S. big vape survey

    McKEGANEY N.; PATTON A.; BARNARD G.; HASEEN F.; HAMILTON T.; KATSAMPOURIS E.; MARZA V.; NOTLEY S.
    Centre for Substance Use Research, Glasgow, UK
    ENDS is a world of near infinite diversity in product design, price, appearance, flavors, nicotine strengths. Whilst there is extensive research on the ENDS category and on individual ENDS products only rarely has any attempt been made to compare...
  8. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 32

    Development of recommendations of descriptive consumer-reported outcome measures (descriptive-CROM) and related definitions in tobacco and nicotine research

    WEI L.(1) on behalf of CORESTA CROM Task Force: CLERC E.(2); SHETTY M.(3); CHREA C.(2); PRASAD K.(3); SARKAR M.(1)
    (1) Altria Client Services LLC, Richmond, VA, USA; (2) Philip Morris International, Neuchâtel, Switzerland; (3) British American Tobacco, Southampton, UK
    Background: The Consumer Reported Outcome Measures (CROM) Consortium Task Force (TF), consisting of academic researchers and members from various tobacco companies, was formed within the Cooperation Centre for Scientific Research Relative to Tobacco...