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  1. CORESTA Meeting, Agronomy/Phytopathology, 2021, Online, AP 08

    An update to the molecular markers used for rapid screening of pathogen resistant plants

    JULIO E.(1); COTUCHEAU J.(1); VOLPATTI R.(1); DECORPS C.(1); VERRON T.(2); CAHOURS X.(2); DORLHAC DE BORNE F.(1)
    (1) Imperial Brands, Leaf Research, Bergerac, France; (2) Imperial Brands, Scientific Research, Paris, France
    Due to cheaper costs associated with next generation sequencing (NGS) technologies, the availability of transcriptomic and genomic information has enabled the characterization of new molecular markers related to important agronomic traits. Today,...
  2. CORESTA Meeting, Agronomy/Phytopathology, 2021, Online, AP 31

    High quality genome assembly of Nicotiana tabacum

    GAYSSANT H.(1); DARNIGE E.(1); COTUCHEAU J.(2); DORLHAC DE BORNE F.(2); JULIO E.(2); ZOUINE M.(1)
    (1) Laboratoire de Recherche en Sciences Végétales (LRSV), Université de Toulouse, CNRS, UPS, Toulouse INP, Castanet-Tolosan, France; (2) Imperial Tobacco Limited and Imperial Brands PLC Companies, Bergerac, France
    Nicotiana tabacum, or cultivated tobacco, is an important plant model whose genome has been explored recently. However, the previous tobacco assemblies based on short reads sequencing showed some flaws. Thanks to new sequencing technologies, the...
  4. CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, AP 13

    Development of codominant markers related to powdery mildew resistance from N. tomentosiformis origin

    JULIO E.(1); MALPICA A.(2); COTUCHEAU J.(1); BACHET S.(2); VOLPATTI R.(1); DECORPS C.(1); DORLHAC DE BORNE F.(1)
    (1) SEITA - Imperial Brands, Leaf Research, Bergerac, France; (2) Bergerac Seeds and Breeding, Bergerac, France
    Powdery mildew is a common tobacco plant fungal disease which can reduce growers' crop yields, particularly in South Africa, Asia and Europe. Three different resistance sources are known, coming from wild tobacco species N. tomentosiformis and N....
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 45

    Meta-analysis of two biomarkers of exposure of tobacco products

    AYALA-FIERRO F.(1); ELAMIN A.(2); FROST-PINEDA K.(3); JIN T.(3); PRASAD G.L.(3); SARKAR M.(4); SCHMIDT E.(3); VERRON T.(5)
    (1) ITG Brands LLC, Greensboro, NC, U.S.A.; (2) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (3) RAI Services Company, Winston-Salem, NC, U.S.A.; (4) Altria Client Services LLC, Richmond, VA, U.S.A.; (5) SEITA - Imperial Brands, Paris, France
    In the context of tobacco products, broadly two types of biomarkers exist, biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH). BoE measure exposure to tobacco constituents, e.g. carbon monoxide (CO) and nicotine equivalents (NEQs)....
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 56

    Perceptions of the relative harm of electronic cigarettes compared with smoking in the U.S.A.: analysis of the Population Assessment of Tobacco and Health (PATH) study data, 2013-2016

    O’CONNELL G.(1); WALELE T.(1); CAHOURS X.(2); THOMPSON J.(1); VERRON T.(2)
    (1) Imperial Tobacco Limited, Bristol, U.K.; (2) SEITA - Imperial Brands, Paris, France
    Electronic cigarettes (e-cigarettes) have been characterised as significantly less harmful than smoked tobacco by an increasing number of public health authorities. Despite this, U.S. adults remain poorly informed about the relative risk of these...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 58

    A consortium approach for consumer-reported outcome measures to assess tobacco- and nicotine-containing products

    ACQUADRO C.(1) on behalf of the CORESTA CROM Task Force: AYALA-FIERRO F.(2); BLACK R.(3); CAHOURS X.(4); CHREA C.(5); CURTIN G.(6); GILES L.(7); McCAFFREY S.(3); PARK C.H.(8); PRASAD K.(9); SHERWOOD N.(10); SHIFFMAN S.(11); SMITH J.(6); SPIES E.(5)
    (1) Mapi Research Trust, Lyon, France; (2) ITG Brands, Greensboro, NC, U.S.A.; (3) Altria Client Services, Richmond, VA, U.S.A.; (4) SEITA - Imperial Brands, Paris, France; (5) Philip Morris Products S.A., Neûchatel, Switzerland; (6) RAIS, Winston-Salem, NC, U.S.A.; (7) JT Int'l SA, Genève, Switzerland; (8) KT&G Research Institute, Daejeon, Republic of Korea; (9) British American Tobacco, Southampton, U.K.; (10) Neil Sherwood Consulting, Commugny, Switzerland; (11) Pinney Associates, Pittsburgh, PA, U.S.A.
    In the tobacco space, consumer-reported outcome measures (CROM) are essential for understanding motivations, subjective effects, and behavior. Such measures have become particularly important with the advent of candidate modified risk tobacco...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, STPOST 65; CORESTA Meeting, Agronomy/Phytopathology, 2019, Victoria Falls, APPOST 15

    Analysis of mainstream cigarette smoke constituents prioritized by the World Health Organization in a core collection of tobacco accessions: variability and correlations

    CAHOURS X.(2); JULIO E.(1); VERRON T.(2); DORLHAC DE BORNE F.(1)
    (1) SEITA - Imperial Brands, Leaf Research, Bergerac, France; (2) SEITA - Imperial Brands, Scientific Research, Paris, France
    Among the different strategies proposed for tobacco regulation, the WHO study group on Tobacco Product Regulation (TobReg) has proposed mandating ceilings on smoke constituents. These constituents were selected according to their potential toxicity,...
  9. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, APPOST 11

    Field trials with low nicotine tobacco varieties developed by conventional breeding technique: first results

    MALPICA A.(1); EVANS W.(2); ARCHIBALD C.(3); SCOTT L.(4); GARWE D.(5); CHAMANGO A.M.Z.(6); DORLHAC de BORNE F.(7); COLARD S.(8)
    (1) Bergerac Seed and Breeding, Bergerac, France; (2) Imperial Tobacco South Africa Pvt. Ltd, Umhlanga, Durban, South Africa; (3) Alliance One International Services, Camberley, Surrey, U.K.; (4) Universal Leaf Tobacco Co., Richmond, VA, U.S.A.; (5) Tobacco Research Board (TRB), Harare, Zimbabwe; (6) Agricultural Research & Extension Trust (ARET), Lilongwe, Malawi; (7) Imperial Tobacco Limited, Bergerac, France; (8) SEITA - Imperial Brands plc, Paris, France
    In 2015, the World Health Organisation (WHO) Study Group on Tobacco Product Regulation (“TobReg”) issued an advisory note recommending a strategy of reducing nicotine in tobacco to substantially lower levels of 0.4 mg/g. In the U.S., the Food and...
  10. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, APPOST 30

    Nicotine reduction and consumer perception: a scientific approach for quantifying possible impact of low nicotine cigarettes on consumer behaviour

    GUO Mengran(1); VERRON T.(1); DORLHAC de BORNE F.(2); PRITCHARD J.(3); COLARD S.(1)
    (1) SEITA - Imperial Brands plc, Paris, France; (2) Imperial Tobacco Limited, Leaf Research, Bergerac, France; (3) Imperial Brands, Bristol, U.K.
    In 2015, the WHO Study Group on Tobacco Product Regulation (TobReg) issued an advisory note recommending a strategy to reduce nicotine in tobacco to levels which would not be sufficient to lead to the development and/or maintenance of addiction. In...