Search Results

390 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 17

    Determination of eight carbonyl compounds in e-liquids for electronic cigarettes by LC-MS/MS

    PAN Lining; LIU Shaofeng; ZHAO Le; YU Jingjing; LIU Kejian; FAN Meijuan; CHEN Li; WANG Hongbo; GUO Junwei
    Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China
    A liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed to simultaneously determine eight carbonyl compounds (formaldehyde, acetaldehyde, acetone, acrolein, propionaldehyde, crotonaldehyde, 2-butanone, butyraldehyde) in...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 26

    Dynamic determination of nicotine and 11 metabolites in brain and blood of rat by simultaneous microdialysis coupled with UHPLC-HRMS

    MAO Jian; SUN Shihao; LU Binbin; LI Peng; LIU Junhui; ZENG Shitong; ZHANG Qidong; CHAI Guobi; XI Hui; ZHANG Jianxun
    Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China
    Nicotine is the most specific cigarette smoke component and plays a key role in tobacco addiction. Nicotine dependence based on neuropharmacology effects is closely associated with nicotine metabolism. Although peripheral metabolism of nicotine has...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 29 (also presented at TSRC 2017)

    Impact of cigar physical variability on cigar exposure using probabilistic risk assessment

    AYALA-FIERRO F.; KOSARAJU K.; STEVENS R.
    ITG Brands LLC, Greensboro, NC, U.S.A.
    Cigars are unique tobacco products of wide variety of sizes: length, diameter and weight, and include large cigars, small cigars (cigarette-like) and cigarillos. The weight of cigars can range widely which influences exposure to cigar constituents,...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 30 (also presented at TSRC 2017)

    Comparison of probability of risk associated with cigar exposure

    KOSARAJU K.; AYALA-FIERRO F.; STEVENS R.
    ITG Brands LLC, Greensboro, NC, U.S.A.
    Cigars are unique tobacco products of variable physical and chemical properties. Limited information is available about exposure to smoke and probability of risk, if any, to smoke constituents. Cigar smokers can be exclusive or dual smokers of cigars...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 62

    Overview of in vitro methods used to assess e-cigarettes based on “Toxicity Testing in 21st Century” principles

    SIMMS L.(1); STEVENSON M.(1); CZEKALA L.(1); TSCHIERSKE N.(1); WALELE T.(2)
    (1) Imperial Tobacco Ltd, Bristol, U.K.; (2) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands
    When the National Academies of Sciences released “Toxicity Testing in the 21st Century: A Vision and a Strategy” a new toxicological paradigm was created, focusing on the use of human cell lines and the disruption of key cellular pathways. In keeping...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 08

    Indoor air quality and surface deposition assessment following use of an open system e-cigarette

    BAUER N.(1); TSCHIERSKE N.(1); O'CONNELL G.(2); CAHOURS X.(3)
    (1) Reemtsma Cigarettenfabriken GmbH (an Imperial Brands PLC Company), Hamburg, Germany; (2) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands; (3) SEITA-Imperial Tobacco Limited, Fleury-les-Aubrais, France
    Electronic cigarette (e-cigarette) nicotine delivery devices are growing in popularity worldwide. Both regulators and public health organisations are beginning to examine potential implications that exposure to exhaled e-cigarette aerosol may have on...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 10

    Methods for characterising morphological and structural variations of cut tobacco in cigarettes during smoking

    WANG Liang(1); YIN Donghong(1); XIE Guoyong(1); LI Bin(2); TAN Xinliang(1); DU Wen(1)
    (1) Hunan Industrial Co., Ltd of CNTC, Research and Development Center, Changsha, Hunan, P.R. China; (2) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China
    The morphological and structural variations of cut tobacco significantly influence the state of a burning cigarette and the formation of smoke constituents. A series of new methods for characterising the micro-structure of cut tobacco, planar...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 12

    Study on vaporisation temperature of electronic cigarette

    CUI Huapeng; ZHAO Le; FAN Meijuan; LIU Shaofeng; CHEN Li; CAI Junlan; QIN Yaqiong; DING Xue; JIANG Zhicai
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China; (2) China Tobacco Zhejiang Industrial Co., Ltd, Hangzhou, Zhejiang, P.R. China
    The vaporisation temperature of electronic cigarettes (e-cigarettes) affects the release and migration of harmful components in e-cigarettes greatly. Therefore a method for measuring the vaporisation temperature was established based on a...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 13

    The comparative assessment of e-cigarettes and cigarettes on cytotoxicity and proinflammatory cytokine secretion level using an air-liquid interface system

    HUA Chenfeng; QIAO Liangjun; KANG Yu; ZHAO Junwei; QIN Yaqiong; CUI Huapeng; SHANG Pingping; LIU Huimin; LI Xiang; XIE Fuwei
    Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China
    Electronic cigarettes (e-cigarettes), as an alternative to combustible cigarettes, have become more and more popular. In this study, the cytotoxic and proinflammatory cytokine secretion response of e-cigarette vapour (e-vapour) and traditional...
  10. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 21

    The use of in vitro human biomarkers from relevant primary cell lines, to assess the effects of increasing nicotine concentration in e-liquids

    SIMMS L.(1); STEVENSON M.(1); CZEKALA L.(1); TSCHIERSKE N.(1); BERG E.(2); WALELE T.(3)
    (1) Imperial Tobacco Ltd, Bristol, U.K.; (2) DiscoverX Corporation, Fremont, CA, U.S.A.; (3) Fontem Ventures B.V. (an Imperial Brands PLC Company), Amsterdam, The Netherlands
    As part of the ongoing stewardship of electronic cigarettes, and in line with the National Academies of Sciences “Toxicity Testing in the 21st Century: A Vision and a Strategy”, Fontem Ventures B.V. have investigated the utility of a series of...