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342 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 27

    Pharmacokinetics of nicotine following the controlled use of a prototype novel tobacco vapour product

    YUKI D.(1,2); SAKAGUCHI C.(1); KIKUCHI A.(1); FUTAMURA Y.(1)
    (1) Japan Tobacco Inc., R&D Group, Scientific Product Assessment Center, Yokohama, Kanagawa, Japan; (2) JT International S.A., Scientific & Regulatory Affairs, Geneva, Switzerland
    The objective of this clinical study was to investigate the pharmacokinetics of nicotine following the use of a prototype novel tobacco vapour (PNTV) product in comparison to a conventional cigarette (CC1). The study was conducted in Japanese healthy ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 43

    Feasibility study of simultaneous determination of particulate and volatile compounds in mainstream cigarette smoke

    KUMAGAI A.; EGUCHI K.; FUKAI Y.
    Japan Tobacco Inc., Product Quality Research Center, Yokohama, Kanagawa, Japan
    This study demonstrates the feasibility of simultaneous determination of tobacco-specific nitrosamines (TSNAs) and volatile organic compounds (VOCs) in mainstream cigarette smoke. WHO TobReg has proposed mandated lowering of nine toxicants in mainstream ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 58

    Contribution of gas-phase combustion to total heat generation from a burning cigarette

    INOUE Y.(1); SUZUKI M.(2)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Kanagawa, Japan; (2) Nagaoka University of Technology, Nagaoka, Niigata, Japan
    Heat release is an important factor in understanding a burning cigarette. Heat releasing reactions are assumed to consist of three categories: pyrolysis, generating char and pyrolysis gas; combustion, generating combustion gas and residue; and gas-phase ...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 59

    Estimating the filling capacity of cut-rolled expanded stem (CRES) from Visible (Vis)–Near infrared (NIR) spectrum of stem

    SHIMIZU W.(1); ISHIHARA K.(1); YAGASHIRA T.(2)
    (1) Japan Tobacco Inc., Leaf Tobacco Research Center, Tochigi, Japan; (2) JT International Germany GmbH, Trier, Germany
    Filling capacity is an important physical characteristic for evaluating cut-rolled expanded stem (CRES) quality and for designing cigarettes. As presented at the CORESTA Congress 2012, we developed a calibration model between Vis-NIR spectra and filling ...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 04

    Development of a method for the estimation of mouth level exposure to nicotine from electronic cigarettes

    KUBOTA T.; SUZUKI T.; SHIBATA T.
    Japan Tobacco Inc., R&D Group, Scientific Product Assessment Center, Yokohama, Kanagawa, Japan
    Mouth level exposure (MLE) assessments are valuable in helping interpret, as well as potentially predict, the results from clinical investigations, such as biomarkers of exposure studies. To date, methods to estimate nicotine-MLE from electronic cigarette ...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 09

    Analysis of metals in e-liquids - reduction of matrix effects

    SHIMAZU A.; MASUGI E.; MIZUNO M.
    Japan Tobacco Inc., Product Quality Research Center, Yokohama, Kanagawa, Japan
    An analytical method for simultaneous determination of various metals in e-cigarette aerosol using inductively coupled plasma mass spectrometry (ICP-MS) was reported at the CORESTA Congress in 2016. In the presence of propylene glycol and glycerol ...