Search Results

356 results

  1. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, ST 03

    Solvent-free extraction method for in vitro testing with tobacco vapor products

    ITO H.; KITAMURA N.
    Japan Tobacco Inc., Scientific Product Assessment Center, Yokohama, Kanagawa, Japan
    Since extracts made with emissions from ENDS and tobacco vapor products (TVP) generally exhibit weak biological responses in commonly used in vitro tests compared to those from conventional cigarettes, it is essential to generate very high...
  2. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 17

    Evaluation of reduction in exposure to selected cigarette smoke constituents after switching to novel tobacco vapor product (NTV) use during a five-day confinement study in Japan

    TAKESHIGE Y.; YUKI D.; NAKAYA K.; FUTAMURA Y.
    Japan Tobacco Inc., Scientific Product Assessment Center, Yokohama, Kanagawa, Japan
    We recently developed a novel tobacco vapor product (NTV) that comprises a battery, a cartridge with a heater and nicotine-free liquid, and a tobacco capsule filled with tobacco blend. Vapor containing nicotine and flavor is produced by aerosol from...
  3. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 18

    Evaluation of subjective effects and product use patterns of novel tobacco vapor product (NTV) use during a five-day confinement study in Japan

    NISHIHARA D.; YUKI D.; NAKAYA K.; TAKESHIGE Y.; FUTAMURA Y.
    Japan Tobacco Inc., Scientific Product Assessment Center, Yokohama, Kanagawa, Japan
    Some authorities have highlighted information relating to the abuse liability of tobacco products as key in reaching regulatory decisions. Although abuse liability should be assessed with multiple factors, one of the essential elements is the...
  4. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 25

    A simplified analytical method for determining metals in e-liquid

    SHIMAZU A.(1); MIZUNO M.(2); NAGAE H.(2)
    (1) Japan Tobacco Inc., Product Quality Research Center, Tokyo, Japan; (2) Japan Tobacco Inc., Product Quality Research Center, Yokohama, Kanagawa, Japan
    An analytical method for simultaneous determination of eight metals in mainstream cigarette smoke using inductively coupled plasma mass spectrometry (ICP-MS) was reported at the Tobacco Science Research Conference (TSRC) in 2009. The method does not...
  5. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 35

    Simultaneous determination analysis of nicotine, propylene glycol, glycerol and menthol in vapor of tobacco vapor products

    MICHIKAWA H.; OMORI F.
    Japan Tobacco Inc., Product Quality Research Center, Yokohama, Kanagawa, Japan
    Recently, in addition to e-cigarettes, tobacco vapor products, such as directly heated products and indirectly heated products, have been gaining popularity in some markets. CORESTA has developed a Recommended Method for simultaneous determination of...
  6. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 36

    Analysis of the TPD2-related flavor compounds in cigarettes by GC-MS/MS and LC-MS/MS

    ORIKATA N.(1); SATO S.(2); TOBITA T.(1); OGAWA T.(1); NINOMIYA M.(1)
    (1) Japan Tobacco Inc., Product Quality Research Center, Yokohama, Kanagawa, Japan; (2) JTI Ökolab, Vienna, Austria
    The new European Union Tobacco Products Directive (TPD2) came into force in May 2016. The European Commission has established a priority list of 15 additives referred to in Article 6 of TPD2. The purpose of this study was to develop quantitative...
  7. CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 37

    Simultaneous determination of sugar alcohols in cigarettes by LC-MS/MS

    OGAWA T.(1); TOBITA T.(1); ORIKATA N.(1); SATO S.(2); NINOMIYA M.(1)
    (1) Japan Tobacco Inc., Product Quality Research Center, Yokohama, Kanagawa, Japan; (2) JTI Ökolab, Vienna, Austria
    Sugar alcohols are used generally and widely as sweeteners and humectants in the food industry. On the other hand, it is known that some sugar alcohols are present in tobacco leaf and tobacco products such as cigarettes. However, there is no method...
  8. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 100

    Comparison of hydrophilic interaction liquid chromatography and reversed-phase separation in untargeted LC/MS analysis of 3D cell cultures exposed to cigarette smoke and aerosols from a novel tobacco vapor product

    TAKANAMI Y.; KITAMURA N.; ITO S.
    Japan Tobacco Inc., Yokohama, Japan
    Aerosols from a novel tobacco vapor product (NTV) generate lower levels of potentially harmful constituents than cigarettes. In vitro cell cultures are expected to exhibit early-phase biological responses to cigarette smoke; a comprehensive analysis...
  9. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 110

    Rapid measurement of phytochemicals in tobacco leaves using fluorescence fingerprint analysis

    NAITO H.(1); TSUTA M.(2); KOIKE T.(1)
    (1) Japan Tobacco Inc., Yokohama, Japan; (2) National Agriculture and Food Research Organization / Food Research Institute, Yokohama, Japan
    Recently, progress has been made in rapid analysis of tobacco leaves. The amounts of water, sugar, and nicotine in tobacco leaves have been measured using near infrared spectroscopy. However, components that have low contents, such as phytochemicals,...