Search Results

356 results

  1. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 21

    Search for low polar non-volatile components characterising tobacco leaves using liquid chromatography / atmospheric pressure chemical ionisation mass spectrometer (LC/APCI-MS)

    ISHIDA N.
    Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Kanagawa 227-8512, Japan
    To discriminate the quality of tobacco growing areas, chemometrics methodology has been applied by using gas chromatography mass spectrometry (GC/MS) or by liquid chromatography electro spray ionisation mass spectrometer (LC/ESI-MS). However, these...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 30

    Application of multidimensional GC in combination with tandem mass spectrometry and accurate mass detection for identification of sulphur compounds in tobacco smoke extract

    MITSUI K.(1); YOSHIMURA Y.(1); OCHIAI N.(2); SASAMOTO K.(2); NAGATA H.(1); DAVID F.(3); SANDRA P.(3)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Japan; (2) Gerstel K.K., Tokyo, Japan; (3) Research Institute for Chromatography, Kortrijk, Belgium
    Tobacco smoke is a highly complex mixture of a wide variety of chemical compounds including sulphur-containing compounds which are present at very low concentrations and have low odour thresholds. From past studies, it is well known that required...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 37

    Good relationship between saliva cotinine kinetics and plasma cotinine kinetics after smoking one cigarette

    YUKI D.; KIKUCHI A.; MIURA N.; KAKEHI A.; ONOZAWA M.
    Japan Tobacco Inc., R&D Group, Product Science Division, Yokohama, Kanagawa, Japan
    This study investigated the relationship between plasma and saliva cotinine kinetics after smoking one cigarette and the relationship between cotinine kinetics and estimated nicotine intake, which was calculated as mouth level exposure (MLE) of...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 41

    Activation of transcription factors in human bronchial epithelial cells exposed to aqueous extracts of mainstream cigarette smoke in vitro

    SEKINE T.; HIRATA T.; MINE T.; FUKANO Y.
    Japan Tobacco Inc., Product Science Division, R&D Group, Yokohama, Japan
    Transcription factors are recognised as important components of signalling cascades controlling all types of normal cellular processes as well as response to external stimulus. Activation of transcription factors can alter the expression of specific...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 49

    Influence of conditioning on NFDPM yields of mentholated cigarettes

    NAKAGAWA A.; MORIYAMA Y.; NARITA T.; TAKAHASHI H.
    Japan Tobacco Inc., Product Quality Research Div., R&D Group, Tokyo, Japan
    When comparing NFDPM yields for mentholated and non-mentholated cigarettes between laboratories, mentholated cigarettes tend to be more variable. The following work was done to identify factors during conditioning which may have an impact on NFDPM...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 57

    Effects of pyrolysis conditions on the formation reaction of 4-aminobiphenyl in non-isothermal pyrolysis of tobacco

    YOSHIDA S.(1,2); KOBAYASHI K.(2)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Japan; (2) Graduate School of Engineering, Yokohama National University, Yokohama, Japan
    4-Aminobiphenyl (4-ABP) is a polycyclic aromatic amine in cigarette smoke. Previous reports indicate that proteinaceous compounds (e.g. amino acids, peptides and proteins) in tobacco can highly contribute to the yield of 4-ABP measured in smoke. In a...
  7. TSRC, Tob. Sci. Res. Conf., 2013, 67, abstr. 25

    Estimation of measurement uncertainty of maleic hydrazide residue in tobacco by ISO method and identification of the dominant contributory components to the estimated uncertainty.

    MIYOSHI M.; KAWAKAMI C.
    Japan Tobacco Inc., Tochigi, Japan
    Measurement uncertainty (MU) is a quantitative indicator of the confidence in the analytical data and describes the range around a measured result within which the true value can be expected to exist with a defined probability. Generally, there are...