TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 05
Assessment of in vitro toxicities demonstrated by total particulate matter (TPM) generated from current market and research reference standard cigarettes using the Bhas-42 promotor cell transformation assay
(1) Scientific & Regulatory Affairs, RAI Services Company, Winston-Salem, NC 27102, USA; (2) MilliporeSigma (BioReliance® Toxicology Testing Services), Rockville, MD 20850, USA
The Bhas 42 cell transformation assay (CTA) has been used to complement standard in vitro testing of tobacco products for understanding downstream biological implications of genetic toxicological changes related to tumor promotion. Investigators have...