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98 results

  1. TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 83

    In vitro toxicity screening of blu electronic cigarette liquids and implications for human exposure

    (1) ITG Brands, Greensboro, NC USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, North Carolina, USA
    The popularity and sales of electronic cigarettes (e-cigs) have increased significantly with thousands of available flavors, many with limited knowledge regarding their toxicity. An initial in vitro toxicological screening was conducted for several...
  2. TSRC, Tob. Sci. Res. Conf., 2014, 68, abstr. 36

    Effects of cigarette smoke condensation under different smoking regimens on human oral epidermoid carcinoma cells

    FAN Ziyan(1); LIU Shanshan(1); LI Zhonghao(1); PANG Yongqiang(1); JIANG Xingyi(1); TANG Gangling(1); ZHAI Niu(2)
    (1) China National Tobacco Quality Supervision & Test Center, Zhengzhou, P.R. China; (2) China Tobacco Gene Research Center, Zhengzhou, P.R. China
    In this study, immortalized human oral cells (oral epidermoid carcinoma cell line KB) was used as an experimental model to assess the cytotoxicity of exposure to cigarette smoke condensates (CSCs) prepared under ISO and HCI smoking regimens. The dose...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 43

    A quantum dot-labelled immunoassay for assessing the in vitro genotoxicity of cigarette smoke based on quantitative detection of γH2AX

    CHEN Huan; LIU Tong; HAN Shulei; ZHANG Xiaotao; HOU Hongwei; HU Qingyuan
    China National Quality Supervision and Test Center, Zhengzhou, P.R. China
    Phosphorylation of histone H2AX (γH2AX) is a sensitive marker of activated DNA damage involving the formation of double-strand breaks. A novel quantum dot-labelled immunoassay was developed for profiling the genetic toxicity of cigarette smoke based...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, STPOST 10

    A prediction model for effects of atmospheric pressure on deliveries of tar and carbon monoxide in mainstream smoke based on ventilation rate of cigarettes

    ZHAO Hui(1); XIONG Wen(1); CHEN Zaigen(2); QU Guofu(1); YANG Liu(3); LI Ying(1); QIN Yunhua(3)
    (1) Hongta Tobacco (Group) Co., Ltd., R&D Center, Yuxi, Yunnan, P.R. China; (2) China National Tobacco Quality Supervision & Test Center, Zhengzhou, Henan, P.R. China; (3) Yunnan Academy of Tobacco Science, Kunming, Yunnan, P.R. China
    The deliveries of components in mainstream cigarette smoke determined under various atmospheric pressures are quite different, especially for tar and carbon monoxide. Multiple smoke analysis laboratories of China are located in high altitude areas,...
  5. CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPT 26 (Poster)

    Determination of CEMA and HEMA in urine of restrictive smokers

    HOU Hong-wei; XIONG Wei; ZHANG Xiao-tao; TANG Gang-ling; HU Qing-yuan
    China National Tobacco Quality Supervision & Test Center, Zhengzhou High-Tech Industrial Development Zone, Zhengzhou, Henan, P.R. China
    Acrylonitrile is a reactive volatile compound, which is cytotoxic, mutagenic and possibly carcinogenic to humans. A major source for the non-occupational exposure to acrylonitrile is tobacco smoke. The major metabolites of acrylonitrile in human...