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313 results

  1. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 06

    Analysis of (S)- and (R)-nicotine in commercial nicotine samples and e-liquids and (R)-nicotine pharmacology

    DULL G.M.(1); MOLDOVEANU S.C.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) R.J. Reynolds Tobacco, Winston-Salem, NC, USA
    Nicotine has been studied extensively because of its presence in tobacco products. Because of its chirality, nicotine can exist in two enantiomeric forms; however, the tobacco plant produces predominantly (S)-nicotine with only a trace of...
  2. TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 21

    Characterization of free radicals in cigarette smoke and e-cigarette aerosols by spin-trapping EPR spectroscopy

    DAVIS M.(1); PROBERT C.C.(2); SMIRNOVA T.(2); SMIRNOV A.(2); PRASAD G.L.(3)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA; (2) North Carolina State University, Raleigh, NC, USA; (3) RAI Services Company, Winston-Salem, NC, USA
    E-cigarettes have gained popularity since their introduction in the market; however, only limited data about free radical content of e-cigarette aerosols and the nature of the radicals formed are available in the literature. The overall goal of this...
  3. TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 019

    Simulated leachables assessment for critical components used in cartridges of electronic nicotine delivery systems

    CULBERT C.(1); WEIDMAN R.(2)
    (1) RAI Services Company, Winston-Salem, NC, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
    Electronic Nicotine Delivery Systems (ENDS) contain e-liquid formulations that are heated to generate aerosols. The potential for chemicals to leach from the device materials into the e-liquid and transfer into the aerosol has been an area of...
  4. CORESTA Congress, Kunming, 2018, Agronomy/Phytopathology Groups, AP 01 (also presented at TSRC 2018)

    FDA advance notice of proposed rulemaking for nicotine level of combusted cigarettes – feasibility for compliance via tobacco plant genetics?

    HIATT E.
    R.J. Reynolds Tobacco Co., Winston-Salem, NC, U.S.A.
    On March 16, 2018, the U.S. Food and Drug Administration (FDA) published an advance notice of proposed rulemaking (ANPRM) entitled “Tobacco Product Standard for Nicotine Level of Combusted Cigarettes.” The publication of an ANPRM solicits information...
  5. TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 006

    Qualitative assessment of flavor ingredients in market electronic nicotine delivery systems

    HUDSON A.G.(1); CULBERT C.G.(2)
    (1) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA; (2) RAI Services Company, Winston-Salem, NC, USA
    As the use of electronic nicotine delivery systems (ENDS) grows, it may be useful to understand the types of flavor compounds that are being added as ingredients to the ENDS currently available on the market. A qualitative analysis of flavor...