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354 results

  1. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 30

    Comparative study of cigarette smoke-induced effects among multiple strains of mice

    MOTOHASHI Y.; SUZUKI H.; OZAKI H.; MINE T.
    Japan Tobacco Inc., R&D Group, Scientific Product Assessment Center, Yokohama, Kanagawa, Japan
    It is known that the effects of cigarette-smoke (CS) exposure on mice are strain-dependent, due to differences in genetic backgrounds. However, the susceptibility of the strains to CS-exposure is inconsistent across reports, probably because of ...
  2. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 31

    Improvement of in-situ slide preparation procedure for semi-automated micronucleus counting system

    ERAMI K.(1); SAWAMOTO Y.(1); YOSHINO K.(1); SOFUNI T.(2)
    (1) Japan Tobacco Inc., Scientific Product Assessment Center, Yokohama, Kanagawa, Japan; (2) Genotoxic Consulting Services, Shiraoka, Saitama, Japan
    In-situ micronucleus (MN) test is an easier-to-use procedure than the traditional way such as a dish preparing approach. Nevertheless, the amount of resources needed for manual counting and the necessity of advanced preparations for reaching consensus of ...
  3. CORESTA Congress, Berlin, 2016, Smoke Science/Product Technology Groups, STPOST 38

    The retention of nicotine from a new type of heated tobacco product in human respiratory tracts

    SUZUKI T.; YUKI D.; KITAGAWA M.; SHIBATA T.
    Japan Tobacco Inc., R&D Group, Scientific Product Assessment Center, Yokohama, Kanagawa, Japan
    Nicotine is the major alkaloid in tobacco leaf and therefore present in tobacco products. Previous studies suggest that absorption sites of nicotine in human respiratory tracts affect nicotine pharmacokinetics. This study investigated the retention of ...
  4. CORESTA Meeting, Agronomy/Phytopathology, 2015, Izmir, Turkey, AP 08

    Molecular mechanism of powdery mildew resistance in tobacco

    ARAI M.; TAJIMA T.; SATO S.; KOMATSU T.; FUJIMURA T
    Japan Tobacco Inc., Leaf Tobacco Research Center, Tochigi, Japan
    Powdery mildew caused by Erysiphe cichoracearum is a major disease of tobacco affecting a wide area including Asia. The Japanese domestic air-cured tobacco cultivar Kokubu (syn. Kou-fan) exhibits extremely high resistance to powdery mildew by recessive ...
  5. CORESTA Meeting, Agronomy/Phytopathology, 2015, Izmir, Turkey, AP 24

    Effect of time and concentration on mortality of the cigarette beetle, Lasioderma serricorne (F.), fumigated with phosphine

    FUKAZAWA N.; TAKAHASHI R.
    Japan Tobacco Inc., Leaf Tobacco Research Center, Tochigi, Japan
    Fumigant efficacy is determined by its concentration (C) and exposure time (t). For typical fumigants such as methyl bromide, the product of C and t is constant (Ct = k) to produce a specific toxic effect for a given insect species. Under these ...
  6. CORESTA Meeting, Agronomy/Phytopathology, 2015, Izmir, Turkey, APPOST 37

    Extraction of volatile flavour compounds from tobacco leaf in a low-density polyethylene membrane

    YOKOI M.(1); SHIMODA M.(2)
    (1) Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Kanagawa, Japan; (2) Kyushu University, Fukuoka, Japan
    Tobacco leaves have various aromas. Many of the volatile flavour compounds in dried leaves have been investigated and reported. Although fresh tobacco leaves have their own aroma, post-harvest processes, such as heating and drying, generate flavour ...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2015, Jeju, ST 22

    Comparison of CORESTA Recommended Methods with the simultaneous determination method of volatile organic compounds and carbonyls in mainstream cigarette smoke

    EGUCHI K.; TOBITA K.
    Japan Tobacco Inc., Product Quantity Research Center, Yokohama, Kanagawa, Japan
    There are several methods to analyse constituents in mainstream cigarette smoke. Some methods have already been validated and others are under development. The simultaneous determination method of volatile organic compounds (VOCs) and carbonyls was ...