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  1. CROM Symposium, Online, 2023, CROM 02

    Challenges and considerations related to human abuse liability testing for tobacco products: opportunities to establish tobacco-specific methods, measures, and evaluation criteria

    VANSICKEL A.R.(1); BAXTER-WRIGHT S.(2)
    (1) Altria Client Services, Richmond, VA, USA; (2) RAI Services Company, Winston-Salem, NC, USA
    The U.S. Food and Drug Administration (FDA) recommends that tobacco product manufacturers provide information regarding the abuse liability of tobacco and nicotine-containing products to support pre-market tobacco, modified risk tobacco product and...
  2. CORESTA Congress, Online, 2022, Agronomy/Phytopathology Groups, AP 21

    Loss of susceptibility loci in tobacco for the development of durable resistance to black shank

    FREDERICK J.; PRAMOD S.; ADAMS A.; XU D.; LUSSO M.
    Altria Client Services LLC, Richmond, VA, U.S.A.
    Black shank root and crown rot disease caused by the soil-borne pathogen, Phytophthora nicotianae, is detrimental to commercial tobacco (Nicotiana tabacum) production and is responsible for significant economic loss. Numerous naturally occurring...
  3. CORESTA Congress, Online, 2022, Agronomy/Phytopathology Groups, AP 43

    The development of ESG programs to help foster social, environmental, and governance initiatives in Altria’s global tobacco supply chain

    IRVING B.; GEOVANNELLO F.
    Altria Client Services LLC, Procurement, Richmond, VA, U.S.A.
    Environmental, social, and governance (ESG) programs can have a positive impact within supply chains of labor-intensive crops, including tobacco, that rely on a dependable labor force and responsible use of crop inputs. Additionally, ESG programs may...
  4. CORESTA Congress, Online, 2022, Agronomy/Phytopathology Groups, AP 51

    Overview of tobacco specific nitrosamines (TSNAs) reduction

    KUDITHIPUDI C.; LUSSO M.; LION K.; XU D.
    Altria Client Services LLC, Product Design and Maintenance, Richmond, VA, U.S.A.
    Tobacco-specific nitrosamines (TSNAs) are a class of toxicants, present in both combustible and smokeless tobacco (ST) products. Of the known TSNAs, nicotine-derived nitrosamine ketone (NNK) and N-nitrosonornicotine (NNN) are carcinogenic and on the...
  5. CORESTA Congress, Online, 2022, Smoke Science/Product Technology Groups, ST 27 (also presented at TSRC 2022)

    Medium/long term variability of moist smokeless tobacco products from the United States marketplace

    MORTON M.; OLEGARIO R.; SENA E.; WAGNER K.A.
    Altria Client Services LLC, Richmond, VA, U.S.A.
    The goal of this work is to characterize temporal variability of moist smokeless tobacco (MST) products from the United States marketplace with respect to harmful and potentially harmful constituents (HPHCs) and selected physical measurements for...
  6. CORESTA Congress, Online, 2022, Smoke Science/Product Technology Groups, ST 30 (also presented at TSRC 2022)

    Modified QuEChERS method for the extraction of nicotine from oral traditional and innovative tobacco products using UPLC-MS/MS

    LOPEZ V.; ALDEEK F.; MILLER J.H.
    Altria Client Services LLC, Research, Development & Regulatory Affairs, Richmond, VA, U.S.A.
    As the tobacco industry continues to emphasize tobacco harm reduction, an array of innovative potentially reduced-risk products have emerged as alternatives to smoking cigarettes. These innovative products include a wide range of smoke-free products...
  7. CORESTA Congress, Online, 2022, Smoke Science/Product Technology Groups, ST 69 (also presented at TSRC 2022)

    An improved method for the determination of carbonyls in cigarette smoke and butyraldehyde co-elution

    JIN X.C.; BALLENTINE R.M.; LI W.; MILLER J.H.
    Altria Client Services LLC, Center for Research and Technology, Richmond, VA, U.S.A.
    Carbonyls, including formaldehyde, acetaldehyde, acetone, acrolein, propionaldehyde crotonaldehyde, methyl ethyl ketone, are included in the FDA established list of harmful and potentially harmful constituents (HPHCs) in tobacco products and tobacco...
  9. TSRC, Tob. Sci. Res. Conf., 2022, 75, abstr. 09 (also presented as presentation at CORESTA 2022)

    An improved method for the determination of carbonyls in cigarette smoke and butyraldehyde co-elution

    JIN X.C.; BALLENTINE R.M.; LI Weiling; MILLER J.H.
    Altria Client Services, Richmond, VA, USA
    Carbonyls, including formaldehyde, acetaldehyde, acetone, acrolein, propionaldehyde crotonaldehyde, methyl ethyl ketone, are included in the FDA established list of Harmful and Potentially Harmful Constituents (HPHC) in tobacco products and tobacco...