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255 results

  1. CORESTA Congress, Online, 2020, Agronomy/Phytopathology Groups, AP 27

    Three-year N-nitrosonornicotine data for stable reduced converter (SRC) dark tobacco crop

    LION K.; LUSSO M.; ADAMS A.; MORRIS W.; DAVIS G.
    Altria Client Services LLC, Research, Development & Regulatory Affairs, Richmond, VA, U.S.A.
    During the past several decades, substantial efforts have been made by the tobacco industry and academic institutions to reduce NNN levels and its precursor nornicotine in tobacco products. Research on the mechanism of nornicotine formation led to...
  2. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 15

    Characterization of on!® nicotine pouches – Part 2: Nicotine dissolution release profiles

    ALDEEK F.; WAGNER K.A.; SMITH C.R.; McCUTCHEON N; GRISEVICH H; SUAREZ C.J.; McFARLANE C.B.; DANIELSON T.L.
    Altria Client Services LLC, Research, Development & Regulatory Affairs, Richmond, VA, U.S.A.
    on!® is an oral tobacco-derived nicotine pouch product that does not contain cut, ground, powdered or leaf tobacco. In order to issue market authorization, the U.S. Food and Drug Administration (FDA) must determine whether the on!® nicotine pouches...
  3. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 20

    Non-targeted analysis using gas chromatography mass spectrometry for evaluation of chemical composition of e-vapor products

    MILLER IV J.H.; SHAH N.H.; NOE M.R.; AGNEW-HEARD K.A.; GARDNER W.P.; PITHAWALLA Y.P.
    Altria Client Services LLC, Richmond, VA, U.S.A.
    The Premarket Tobacco Product Applications (PMTA) guidance issued by the FDA for electronic nicotine delivery systems (ENDS) recommends that in addition to other stability information, manufacturers submit chemical changes (e.g. aerosol constituents)...
  4. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 25

    Human abuse liability assessment of tobacco and nicotine products: considerations to meet current regulatory recommendations

    BAXTER S.(1); VANSICKEL A.(2); SHERWOOD N.(3); CAMPBELL L.(1); KONG M.(4)
    (1) RAI Services Company, Winston Salem, NC, U.S.A.; (2) Altria Client Services, Richmond, VA, U.S.A.; (3) Neil Sherwood Consulting, Nyon, Switzerland; (4) Altasciences Clinical Research, Laval, QC, Canada
    The U.S. Food and Drug Administration (FDA) recommends that tobacco product manufacturers provide information regarding the abuse liability of tobacco and nicotine-containing products to support pre-market tobacco, modified risk tobacco product and...
  5. CORESTA Congress, Online, 2020, Smoke Science/Product Technology Groups, ST 29

    Comparison of reference cigarette variability, smoke yields, and filler HPHC content of 1R6F and 3R4F

    MORTON M.J.; BLAKE T.L.; WAGNER K.A.
    Altria Client Services LLC, Richmond, VA, U.S.A.
    Reference cigarettes have a long history of use in the cigarette industry as quality control monitors, model cigarette systems, and analytical method development tools. The University of Kentucky’s Center for Tobacco Reference Products 3R4F has been...