1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 08

    Effects of smoking parameters on aerosol delivery of next generation of Heated Tobacco Products (HTPs)

    JIN S.J.; LIM G.H.; SHIN G.W.; SHIN S.H.; LEE J.M.
    KT&G Research Institute, Daejeon, South Korea
    In recent years there have been many changes in the cigarette market. Cigarette users are accepting novel products along with conventional cigarettes. These novel products are sometimes referred to as next generation products (NGPs), and include items ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 09

    The ABOUT™ Toolbox: toward the development of consumer-reported outcome measures that matter

    CHREA C.(1); SPIES E.(1); AFOLALU E.(1); BACSO A.(1); CLERC E.(1); MAINY N.(1); BINGGELI P.(1); WEITKUNAT R.(1); ACQUADRO C.(2); SALZBERGER T.(3); CANO S.(4); ABETZ-WEBB L.(5); ROSE J.(6)
    (1) PMI R&D, Philip Morris Products S.A., Neuchatel, Switzerland; (2) Mapi, an ICON plc Company, Lyon, France; (3) University of Economics and Business, Vienna, Austria; (4) ScaleReport, Ltd, Stotfold, U.K.; (5) Patient-Centered Outcomes Assessments, Ltd, Macclesfield Cheshire, U.K.; (6) Rose Research Center, Raleigh, U.S.A.
    Tobacco harm reduction promotes the substitution of reduced-risk products (RRPs) for cigarettes by adult smokers who would otherwise continue to smoke, while preventing RRP initiation among non-users. To operationalize this public health strategy, there ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 10

    Development of the ABOUT™–Health & Functioning: results from the preparatory phase

    SPIES E.(1); BACSO A.(1); CHREA C.(1); ABETZ-WEBB L.(2); AFOLALU E.(1); CLERC E.(1); WEITKUNAT R.(1)
    (1) PMI R&D, Philip Morris Products S.A., Neuchatel, Switzerland; (2) Patient-Centered Outcomes Assessments, Ltd, Macclesfield Cheshire, U.K.
    Switching cigarette smokers to significantly less harmful tobacco or nicotine products, or reduced-risk products (RRPs), has been recognized as a valuable and promising approach to reduce smoking-related population harm. Measuring self-reported experience ...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 11

    Development and validation of the ABOUT™–Dependence measurement instrument to assess perceived dependence on tobacco and nicotine products

    AFOLALU E.(1); CHREA C.(1); SALZBERGER T.(2); ABETZ-WEBB L.(3); CANO S.(4); WEITKUNAT R.(1); ROSE J.(5)
    (1) PMI R&D, Philip Morris Products S.A., Neuchatel, Switzerland; (2) University of Economics and Business, Vienna, Austria; (3) Patient-Centered Outcomes Assessments, Ltd, Macclesfield Cheshire, U.K.; (4) Modus Outcomes, Letchworth Garden City, U.K.; (5) Rose Research Center, Raleigh, U.S.A.
    The development of the ABOUT™–Dependence measurement instrument was initiated to enable assessment of perceived dependence associated with the use of different tobacco and nicotine products (TNPs) and in users of multiple TNPs. We initially developed a ...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 12

    Review of current methodologies in evaluating abuse liability of nicotine and tobacco products in the U.S. regulatory environment

    EVANS S.(1); KONG M.C.(2); CAMPBELL L.(2); SHERWOOD N.(3); PRASAD K.(4)
    (1) Turning Point Brands, Louisville, KY, U.S.A.; (2) Altasciences Clinical Research, Laval, Canada; (3) Neil Sherwood Consulting, Nyon, Switzerland; (4) British American Tobacco, R&D, Millbrook, Southampton, U.K.
    Traditional definitions of abuse and misuse do not apply to a consumer product such as tobacco that consumers essentially use ‘as intended’. In contrast to pharmaceutical products, a guidance for abuse liability testing of nicotine and tobacco products ...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 13

    Importance of e-liquid preparation and stability characterization for a combinatorial safety assessment approach of flavors in e-liquids

    GLABASNIA A.(1); DIANA P.(1); SMITH C.(2); MILLER J.H.(2); BIASIOLI M.(1); FRAUENDORFER F.(1); SCIUSCIO D.(1); MARTIN E.(1); POSPISIL P.(1); GUY P.(1); VANSCHEEUWIJCK P.(1); HOENG J.(1); KUMAR A.(2); LEE K.M.(2)
    (1) PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (2) Altria Client Services LLC, Richmond, VA, U.S.A.
    Numerous flavorings are generally recognized as safe for use in food, but there is limited information available to evaluate their potential toxicity by inhalation. Consequently, gaining information on individual flavor safety levels is of significant ...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 14

    Study on capillary-evaporation effect in porous medium of electronic cigarettes

    GAO Yihan(1); SHEN Yi(1); LI Dian(2); LU Li(2); LI Zhihua(2); WU Jinlu(3); GAO Naiping(3)
    (1) Shanghai New Tobacco Product Research Institute, Shanghai, P.R. China; (2) China Tobacco Guangxi Industrial Co., Ltd., Nanning, P.R. China; (3) Tongji University, Shanghai, P.R. China
    In order to study the capillary-evaporation effect in the porous medium of electronic cigarettes, a theoretical model was established to simulate the heat and mass transfer process in the heating zone of e-cigarettes. Based on the similarity principle, a ...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 15

    Crystal structure of nicotine gentisate and its permeability in pig buccal mucosa

    YANG Ji; MIAO Mingming; CHEN Yongkuan; LIU Zhihua; ZHAO Yang; WU Yiqin; LIU Chunbo; YANG Liu; ZHAO Hui; SHEN Qinpeng; DUAN Yuanxing; GONG Xiaowei
    R&D Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China
    Nicotine compound salt has been widely concerned recently with the continuous expansion of the e-cigarette market. Synthetic nicotine organic acid salt or nicotine complex, instead of monomeric nicotine, is used in the formulation of the next generation ...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 16

    Selected harmful or potentially harmful constituent yields in the aerosol of commercial closed systems electronic cigarettes

    KORNELIOU A.; JACCARD G.; BELUSHKIN M.; TAFIN DJOKO D.; ESPOSITO M.; JEANNET C.; LAZZERINI M.
    PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland
    Over the past few years, electronic cigarettes have rapidly evolved and have been introduced in multiple markets across the world. They are thought to be a potentially less harmful alternative to cigarettes, as they heat a liquid to generate the aerosol ...
  10. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 17

    Comparison of in vitro toxicity of heated tobacco products and combustible cigarettes

    JANG M.; PARK C.H.; YOO J.H.; GWAK H.M.; SOHN H.O.
    KT&G Research Institute, Daejeon, South Korea
    In recent years, the paradigm of the tobacco industry has been changing with the development of heated tobacco products (HTPs) that have a similar taste to cigarettes but significantly reduce the amount of smoke components. The purpose of this study was ...