1. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 18

    Human precision-cut lung slices as a screening tool: increased throughput, cryopreservation, and detection of DNA adducts for next generation tobacco product evaluation

    BEHRSING H.P.(1); DESAI P.(1); AMIN K.(2); BALBO S.(3); HECHT S.S.(2); SHEEHAN D.(1); CASTRO N.(1); ALLEN D.(4)
    (1) Institute for In Vitro Sciences, Inc., Gaithersburg, MD, U.S.A.; (2) University of Minnesota, Division of Environmental Health Sciences, Minneapolis, MN, U.S.A.; (3) University of Minnesota, Department of Laboratory Medicine and Pathology, Minneapolis, MN, U.S.A.; (4) Integrated Laboratory Systems, Inc., Morrisville, NC, U.S.A.
    Human-relevant, in vitro/ex vivo assays are considered an ethical and economically viable manner by which to screen the many chemicals requiring hazard assessment, such as next generation tobacco product (NGTP) ingredients. Human precision-cut lung slices ...
  2. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 19

    In vitro biological impact evaluation of whole cigarette smoke by using pathway-based approach

    CHEN H.(1,2); CHEN X.(1,2); SHEN Y.(3); LIU F.(1,2); YIN X.(1); LIU L.(1); TIMKO M.(4); QI H.(5); FAN L.(1,2,3)
    (1) Institute of Crop Science, Zhejiang University, Hangzhou, P.R. China; (2) Research Center for Air Pollution and Health, Zhejiang University, Hangzhou, P.R. China; (3) Institute of Bioinformatics, Zhejiang University, Hangzhou, P.R. China; (4) Department of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, VA, U.S.A.; (5) Department of Pathology and Pathophysiology, School of Basic Medical Sciences, Zhejiang University, Hangzhou, P.R. China
    Harm-reduced cigarettes have been greatly developed to minimize the negative impact of smoking on health. However, the practical effects of such products are still under debate. Along with the application of high-throughput sequencing technologies (such ...
  3. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 20

    On the scientific value and practical utility of the comparative tests of nicotine-free aerosols in vitro and in vivo

    TROFIMOV A.V.(1); MENSHOV V.A.(1); BERDNIKOVA N.G.(2); YABLONSKAYA O.I.(1)
    (1) Emanuel Institute of Biochemical Physics, RAS, Moscow, Russia; (2) I.M. Sechenov First Moscow State Medical University, Moscow, Russia
    The presence of nicotine in emissions from conventional and electronic cigarettes is an important physiological and associative factor combining these two classes of products. Besides a comparable nicotine delivery, according to other characteristics, ...
  4. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 21

    A model based on cigarette density segmentation method for predicting burning cone drop rate of slim cigarettes

    TAN Chao; WANG Shitai; JIN Yong; CHEN Qian; TAN Haifeng; LI Ke; FAN Hongmei; LIU Qi; LI Rui; YU Saibo
    China Tobacco Hunan Industrial Co., Ltd. of CNTC, Hunan, P.R. China
    Burning cone drop is a potential safety problem and quality defect for slim cigarettes. In order to conveniently monitor the burning cone drop rate, a model based on cigarette density segmentation method was established and used for predicting the burning ...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 22

    Study of combustion patterns for ignition propensity test using several kinds of substrates and cigarettes

    LEE D.H.; KIM Y.S.; SHIN H.J.; LEE M.Y.
    KT&G Research Institute, Daejeon, South Korea
    The ignition propensity of cigarettes can be measured in accordance with ISO 12863:2010. It recommends the use of Whatman No. 2 filter paper as a substrate. Actually most laboratories use this filter paper and there may be a need to replace Whatman No. 2 ...
  6. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 23 (also presented at TSRC 2019)

    Functional filter plug wrap paper for control of the thermal energy of the aerosol from heated tobacco products (HTPs)

    LINDNER M.; LEICHSENRING N.
    (1) TANNPAPIER GmbH, Traun, Austria; (2) Hauni Maschinenbau GmbH, Hamburg, Germany
    Next generation products, which include all kinds of e-vapour items as well as heated tobacco products (HTPs or “heat sticks”), have successfully entered the tobacco market in addition to conventionally combustible cigarettes. From the basic geometrical ...
  7. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 26

    Digital evaluation of tobacco style and quality by using a support vector machine algorithm with thermal analysis spectra

    LI Qiaoling(1); YIN Chao(2); ZHENG Quanxing(1); YU Yumei(1); LIU Xiucai(1); DENG Xiaohua(1); ZHANG Tinggui(1); ZHONG Jiawei(1); WANG Le(3); XU Hanchun(1); LIN Kai(1); MA Pengfei(1); HUANG Chaozhang(1); LI Bin(3); WU Anan(2)
    (1) Technology Center, China Tobacco Fujian Industrial Co., Ltd., Xiamen, Fujian, P.R. China; (2) College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian, P.R. China; (3) Key Laboratory of Tobacco Processing Technology of CNTC, Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R. China
    In the processes of tobacco blend design and product maintenance of cigarettes, the evaluation of tobacco style and quality is very important. At present, the evaluation method mainly relies on artificial sensory analysis, which is subjective and ...
  8. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 27

    Determination of petroleum ether extracts in flue-cured tobacco leaves by NIR combined with random frog wavelength selection method

    QIU Changgui(1,2); LIU Ze(3); CHEN Shi(4); LIU Jing(1,2); WANG Jiajun(3); ZHANG Wen(1,2); YANG Panpan(1,2)
    (1) Yunnan Reascend Tobacco Technology (Group) Co., Ltd., Kunming, P.R. China; (2) Yunnan Comtestor Company, Kunming, P.R. China; (3) Technology Center, China Tobacco Yunnan Industrial Co., Ltd., Kunming, P.R. China; (4) Bijie Cigarette Factory, China Tobacco Guizhou Industrial Co., Ltd., Bijie, P.R. China
    In order to improve the prediction accuracy and model stability for quantitative calibration in near infrared spectroscopy, the random frog wavelength selection method combined with partial least squares (PLS) was employed to establish the prediction ...
  9. CORESTA Meeting, Smoke Science/Product Technology, 2019, Hamburg, ST 28

    Simultaneous determination of 20 amino acids in tobacco leaves by multiple heart-cut two-dimensional liquid chromatography

    WANG Yangzhong; QI Dawei; WU Da; LIU Baizhan
    Technology Center, Shanghai Tobacco Group Co., Ltd., Shanghai, P.R. China
    Amino acids are important aroma precursors in tobacco. They can react with reducing sugar in the processes of tobacco curing, aging or smoking, which is called the Maillard reaction. Various heterocyclic aroma compounds are generated in this reaction, ...