In April 2019 an interlaboratory study was initiated in order to assess the stability of the four CORESTA Reference Products (CRPs) manufactured in 2016, and to provide repeatability (r) and reproducibility (R) results and z-scores to support laboratory accreditation. The participating laboratories reported the levels of nicotine, pH, moisture (oven volatiles), and tobacco specific nitrosamines (TSNAs) in the CRPs using CORESTA Recommended Methods (CRMs). Tabulated data are presented along with repeatability (r), reproducibility (R) estimates and z-scores.

The results from this 2019 stability analysis generally compared well to the 2016 stability analyses.  The only statistically significant difference from the 2016 results was an increase in moisture in CRP3.1, similar to what had been previously observed with CRP3 from the 2009 CRPs.

Please note that the studies on the CRPs produced in 2009 are covered in the reports prior and including 2015.