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Recommended Methods current

No. 102 - Determination of Tobacco-Specific Nitrosamines in E-Liquid by LC-MS/MS

January 2023 Ref. EVAP-304-2-CRM-102

This Recommended Method is applicable to the determination of tobacco-specific nitrosamines (TSNAs) in electronic cigarette liquids (e-liquids). The TSNAs determined with this method are N-nitrosonornicotine (NNN), 4‑(N‑methylnitrosoamino)-1-(3-pyridyl)-1-butanone (NNK), N-nitrosoanatabine (NAT), and N-nitrosoanabasine (NAB). The e-liquids used may be of any flavour, including extracted tobacco-derived flavours.

 

Related documents

CRM 75 - Determination of Tobacco-Specific Nitrosamines in Mainstream Smoke by LC-MS/MS (September 2022)

CRM 72 - Determination of Tobacco-Specific Nitrosamines in Tobacco and Tobacco Products by LC-MS/MS (December 2021)

Report - 2021 Collaborative Study for the Determination of Tobacco-Specific Nitrosamines in E-Liquids (November 2022)

Guide 18 - Sample Handling and Sample Collection of E-Cigarettes and E-Vapour Generating Products (July 2021)