Recommended Methods current

No. 72 - Determination of Tobacco Specific Nitrosamines in Tobacco and Tobacco Products by LC-MS/MS

(CRM developed into ISO 21766)

July 2017 - fourth edition Ref. TTPA-126-2-CRM-72

This Recommended Method is applicable to the determination of TSNAs in ground tobacco, cigarette filler, cigar filler, and smokeless tobacco products (e.g. moist snuff, snus, chewing tobacco and dry snuff). The TSNAs determined with this method are: N-nitrosonornicotine (NNN), 4-(N-methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), N-nitrosoanatabine (NAT), and N-nitrosoanabasine (NAB).

Related documents

Report - 2017 Collaborative Study on TSNA, pH, and Moisture (Oven Volatiles) (July 2017)

Report - CORESTA Reference Products (Smokeless Tobacco) - 2015 Analysis (December 2015)

Report - 2009 Collaborative Study (Smokeless Tobacco r&R Study) (July 2010 - updated Jan 2016)

Guide 11 - Technical Guideline for Sample Handling of Smokeless Tobacco and Smokeless Tobacco Products (May 2020)