No. 72 - Determination of Tobacco Specific Nitrosamines in Tobacco and Tobacco Products by LC-MS/MS
(CRM being developed into ISO Project 21766)
This Recommended Method is applicable to the determination of TSNAs in ground tobacco, cigarette filler, cigar filler, and smokeless tobacco products (e.g. moist snuff, snus, chewing tobacco and dry snuff). The TSNAs determined with this method are: N-nitrosonornicotine (NNN), 4-(N-methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), N-nitrosoanatabine (NAT), and N-nitrosoanabasine (NAB).