A Review of Aerosol Exposure Systems Relative to the Analysis of Cytotoxicity
IVT Technical Report
The In Vitro Toxicity Testing Sub-Group considered the evolving field of aerosol exposure research. Given the combination of exposure parameters and biological endpoints being deployed, it was considered a high priority to assess these systems and contextualize the responses obtained.
Twelve global companies met to discuss this topic and formulate an aligned approach. A detailed and comprehensive survey was conducted on over 40 parameters ranging from aerosol generation, dilution and data analysis across eight geographically independent laboratories.
The results from the survey provided awareness of the exposure systems, parameters and nuances, that may be of substantial benefit to scientists in intersecting fields and in the development of harmonized approaches.
CRM 81 - Routine Analytical Machine for E-Cigarette Aerosol Generation and Collection - Definitions and Standard Conditions (June 2015)
Report - A survey of aerosol exposure systems relative to the analysis of cytotoxicity: A Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA) perspective (July 2021)