TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 61
Bridging cardiovascular in vitro and in vivo models
R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA
To better understand the impact cigarette smoking has on cardiovascular disease, in vivo and in vitro models have been explored. First, atherosclerosis was assessed in the aorta of apoE knockout mice. ApoE is a gene involved in lipoprotein clearance....