Bull. ARN, 2006, p. 74-88., ISSN.1146-6200.
Heme oxygenase-1 prevents airways mucus secretion induced by cigarette smoke in rats
INSERM U700 Epidemiologie, Fac. de Médecine Xavier Bichat, Paris, France
Mucus hypersecretion is an important feature of chronic obstructive pulmonary disease (COPD). Inflammation and/or oxidative stress mediated phosphorylation of the epidermal growth factor receptor (EGFR) plays a central role in this phenomenon. We...