CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPT 22
Development of biomarkers of effect from chronic tobacco usage. Part 1: Study design and biomarkers of exposure
R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA
To assess the effects of chronic exposure to combustible and non-combustible tobacco product use, a single site, cross-sectional clinical study was conducted. Three cohorts of healthy males (40/cohort, 35-60 years) were enrolled: long-term smokers...