CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, ST 18
An adverse outcome pathway for oxidative stress in plaque formation
(1) RAI Services Company, Winston Salem, NC, U.S.A.; (2) BAT Investments Limited, R&D Centre, Southampton, U.K.
Adverse outcome pathways (AOPs) have been developed as risk assessment tool for regulatory applications. These AOPs describe a logical mechanistic sequence of events, starting with a Molecular Initiating Event (MIE), and ultimately leading to a...