TSRC, Tob. Sci. Res. Conf., 2009, 63, abstr. 72
Enantiomer composition of nornicotine determined by nicotine demethylation
University of Kentucky, Dept. of Plant & Soil Sciences, Lexington, KY, USA
Nornicotine, one of four main alkaloids in tobacco, is the major precursor of N'- nitrosonornicotine (NNN). Nornicotine is present in both R- and S- enantiomer in tobacco and each forms the corresponding NNN enantiomer. CYP82E4 (E4) and CYP82E5 (E5)...