CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 46
Validation of an in vitro test battery to evaluate smokeless tobacco products
(1) Charles River Laboratories, Genetic and In Vitro Toxicology, Skokie, IL, U.S.A.; (2) Charles River Laboratories, Analytical Chemistry, Ashland, OH, U.S.A.
Evaluating potential cytotoxicity and genotoxicity of smokeless tobacco products poses unique challenges for in vitro testing. Each product is a complex mixture of vegetable matter, and may include a packaging component as part of the final product....