CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 49
Assessment of alternative cell lines for adoption within the OECD TG 129 for cytotoxicity determination
(1) Reemtsma Cigarettenfabriken GmbH, an Imperial Brands PLC Company, Hamburg, Germany; (2) Imperial Brands PLC, Bristol, U.K.
Neutral red uptake assay (NRU), part of the in vitro CORESTA test “battery” is one of the most commonly used cytotoxicity assays for the evaluation tobacco and next generation products (NGPs). OECD TG 129 guideline for the NRU assay was...