CORESTA Meeting, Smoke Science/Product Technology, 2021, Online, ST 43
Quantitative analysis of NNN in plasma: a suitable alternative to urinary determination to assess the exposure to this important toxicant
PLUYM N.(1); SIBUL F.(1); JIN X.(2); EDMISTON J.(2); SARKAR M.(2); SCHERER G.(1); SCHERER M.(1)
(1) ABF Analytisch-Biologisches Forschungslabor GmbH, Planegg, Germany; (2) Altria Client Services LLC, Center for Research & Technology, Richmond, VA, U.S.A.
N-Nitrosonornicotine (NNN) is classified as a Group 1 carcinogen by the International Agency for Research on Cancer. Urinary NNN has often been used as a biomarker of exposure. However, urinary NNN excretion is highly variable, possibly due to...