CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 49
Use of chiroptical spectroscopy to determine the ionisation status of (S)-nicotine in electronic cigarette formulations and snus
British American Tobacco, Group R&D, Southampton, U.K.
In the vicinity of neutral pH, nicotine is equilibrated between unprotonated and monoprotonated states. The equilibrium is best described by the acid dissociation constant (Ka) and its logarithmic function known as pKa which in non-aqueous solution...