CORESTA Congress, Paris, 2006, SS 19
Changes in the TSNA content of cigarette filler and mainstream smoke determined using an improved LC/MS/MS method
Labstat International Inc., Kitchener, ON, Canada
An improved LC-MS/MS method for the determination of tobacco specific nitrosamines has been developed, utilizing four internal deuterated standards instead of two. This was found to be necessary due to an analyte dependent sample matrix effect, which...