TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 22
Cell transformation activity of cigarette smoke condensate in Bhas 42 ASSAY.
(1) BioReliance Corp Rockville, MD, USA; (2) University of Kentucky Medical Center, Lexington, KY, USA
Cell transformation assays have been commonly used to predict chemical carcinogenicity. Using v-Ha-ras transfected BALB/c3T3 (Bhas 42) cells, Sasaki and coworkers (2010, 2011) have recently validated a sensitive short-term assay that simulates the...