Tobacco Science & Technology, 2004, 3, p.16-24, ISSN.1002-0861 Configuration programming of MVME162 board in new PASSIM cigarette making and tipping machine combination YU DE-ZHI; SHEN YUE; YANG TIAN-TAO Shifang Cigarette Factory, Shifang, Sichuan, China
Bull. ARN, 2006, p. 74-88., ISSN.1146-6200. Heme oxygenase-1 prevents airways mucus secretion induced by cigarette smoke in rats ALMOKI A.; GUENEGOU A.; GOLDA S. INSERM U700 Epidemiologie, Fac. de Médecine Xavier Bichat, Paris, France Mucus hypersecretion is an important feature of chronic obstructive pulmonary disease (COPD). Inflammation and/or oxidative stress mediated phosphorylation of the epidermal growth factor receptor (EGFR) plays a central role in this phenomenon. We...
Bull. ARN, 2006, p. 25-39., ISSN.1146-6200. Treatment of pulmonary arterial hypertension with DHEA:temporal aspects DEBONNEUIL E.; BAULIEU E.E. INSERM U788, Kremlin Bicêtre, France Previous work has shown that DHEA prevents and treats pulmonary arterial hypertension in rats provoked by three weeks of hypoxia. In this laboratory we have installed hypoxia chambers and confirmed this finding, which we have also extended to the...
Bull. ARN, 2006, p. 40-6., ISSN.1146-6200. DHEA effects on pulmonary arterial cells under hypoxia DESSOUROUX A.; BAULIEU E.E. INSERM U788, Kremlin Bicêtre, France The aim of this project is to find molecular targets of DHEA in pulmonary arterial smooth muscle cells under hypoxia during thirty minutes until twenty-four hours. This work has begun after previous works showing that DHEA decreases Pulmonary...
Bull. ARN, 2006, p. 56-73., ISSN.1146-6200. Association of lung function decline with the microsatellite polymorphism in the heme oxygenase-1 gene promoter, in a general population sample. Results from the European Community Respiratory Health Survey (ECRHS), France GUENEGOU A.; LEYNAERT B.; NEUKIRCH F. INSERM U700 Epidemiologie, Fac. de Médecine Xavier Bichat, Paris, France Heme oxygenase (HO-1) acts against oxidants which are thought to play a major role in the pathogenesis of chronic obstructive pulmonary disease (COPD), characterised by impaired lung function. A (GT)n repeat polymorphism in the HO-1 gene promoter can...
Bull. ARN, 2006, 47-55., ISSN.1146-6200. Nicotine, cigarette smoke and Parkinson's disease HILD A.; MICHEL P.; MARCHAND V. INSERM, UMR 679, Neurologie et Thérapeutique Expérimentale, France The prevalence of Parkinson's disease (PD) is lower in the population of smokers than in nonsmokers. This led us initially to analyze the neuroprotective potential of nicotine, the main alkaloid from tobacco leaves, that of cigarette smoke and of the...
Bull. ARN, 2004, p. 23-41., ISSN.1146-6200. Role of the interaction between diesel particulate matter and cigarette smoke in the pathophysiology of chronic obstructive pulmonary disease (COPD) LANONE S.; AMATA N.; BACHOUAL R.; AUBIER M.; BOCZKOWSKI J. INSERM U408, Faculté Xavier Bichat, Paris, France Chronic obstructive pulmonary disease (COPD) is a disease state characterized by airflow limitation that is not fully reversible, leading to respiratory insufficiency. Flow limitation is secondary to the remodeling of the pulmonary parenchyma (called...
Bull. ARN, 2004, p. 42-53., ISSN.1146-6200. Nicotinic receptors and cohesion of the bronchial epithelium TOURNIER J-M.; BIREMBAUT P. INSERM UMRS 514 - Université de Reims Champagne-Ardennes, Reims, France The bronchial epithelium covers the surface of the proximal airways and represents a barrier between inhaled air and the bronchial submucosa. The epithelium function as a protective barrier depends upon the mucociliary system which traps and...
Bull. ARN, 2001, p. 37-46., ISSN.1146-6200. Nicotinic receptors and repair of the bronchial epithelium TOURNIER J-M.; LEBARGY F.; BIREMBAUT P. INSERM UMRS 514 - Université de Reims Champagne-Ardennes, Reims, France When injured, the bronchial epithelium initiates a wound healing process in order to rapidly restore the integrity of the epithelial barrier. During the epithelial repair, the migration of cells located at the wound edge and rearrangement of...
Bull. Spec. CORESTA Congress, Harare 1994, p. 187, S 12 Mass fragmentographic determination of polycyclic aromatic hydrocarbons (PAH) in cigarette smoke condensates CHRISTAKOPOULOS A.; ISAKSSON C.; CURVALL M. Reserca AB, Stockholm - Sweden. More than 4000 compounds have been identified in cigarette smoke and about 80-100 of them are PAHs. They are primarily formed by pyrosynthesis via highly reactive C,H-radicals which result from thermal degradation of nonvolatile organic tobacco...