CORESTA Meeting, Smoke Science/Product Technology, 2011, Graz, STPOST 06
Evaluation of cigarette smoke-induced cell transformation using three in vitro cell transformation assays
(1) R.J. Reynolds Tobacco Co., R&D, Winston-Salem, NC, USA; (2) BioReliance Corporation, Rockville, MD, USA
Cell transformation assays (CTA) detect phenotypic changes associated with neoplastic transformation and available evidence suggests in vitro cell transformation may stimulate early components of the multistage process of carcinogenesis. Moreover,...