TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 015 (also presented at CORESTA 2018)
Genotoxicity evaluation of tobacco and nicotine delivery products: Part 2. In vitro micronucleus assay
LEVERETTE R.(1); BOMBICK B.(1); FOWLER K.(1); BREHENY D.(2); GACA M.(2); THORNE D.(2); CLEMENTS J.(3); McENANEY S.(3); WHITWELL J.(3)
(1) RAI Services Company, Winston-Salem, NC, USA; (2) British American Tobacco (Investments) Ltd., Southampton, UK; (3) Covance Laboratories Ltd, Harrogate, UK
In vitro studies have been widely used to support toxicological evaluations of chemicals and complex mixtures including cigarette smoke. In this study a variety of test matrices from tobacco and nicotine delivery products were assessed against a 3R4F...