Bull. ARN, 2000, p. 44-57., ISSN.1146-6200.
(-)-nicotine but not (-)-cotinine protects dopaminergic neurons from neurodegeneration in Parkinsonian syndroms
INSERM U289, Hôpital de la Salpétrière, Paris, France
Epidemiological studies show a lower incidence of Parkinson's disease for smokers than for non smokers, suggesting that a component in cigarette smoke protects dopaminergic neurons against nigrostriatal degeneration. In the present study we examined...