CORESTA Congress, Sapporo, 2012, Plenary Session, Invited Paper 1
Genetic polymorphism of CYP2A6 is one of the potential factors determining tobacco-relatedcancer risk
Graduate School of Pharmaceutical Sciences, Hokkaido University, Japan
While we studied pharmacokinetics of SM-12502 which was under development as an anti-PAF agent, we found three subjects showing a slow metabolic phenotype in its pharmacokinetics. Analyzing the genes for CYP2A6 from the three subjects, we...