CORESTA Meeting, Smoke Science/Product Technology, 2023, Cancun, STPOST 05
Identification of a novel mode of action of vanillin derivative compound veratraldehyde
Japan Tobacco Inc., Scientific Product Assessment Center, Yokohama, Kanagawa, Japan
Compounds that test positive in in vitro micronucleus tests (MNTs) need to be followed up with in vivo MNTs. However, it is common for these compounds to test negative in in vivo MNTs, known as “misleading positives.” To reduce in vivo follow-up...