The recovery and retention of highly volatile organic compounds is strongly influenced by the environmental conditions at the time of collection. Highly volatile compounds in cigarette smoke can be collected using gas collection bags, akin to the collection of air samples. Alternatively, these compounds can be trapped in solvents at very low temperatures using impingers. We developed two methods for a selected number of highly volatile organics. One method utilizes the trapping of the compounds at -70°C and the other used gas sample bags at room temperature. This study compared the collection efficiency of these two methods. Several cigarettes with different levels of TPM were compared using the HCA and the ISO smoking regime. The talk will present comparison data, conclusions and recommendations.