Peanut root-knot nematode, Meloidogne arenaria, is a serious problem on vegetables and peanuts in Georgia. Georgia grows about 500,000 acres of peanuts annually and peanuts are rotated with vegetable crops and tobacco. A field at the University of Georgia Bowen Farm was diagnosed to have M. arenaria and demonstrated to cause severe damage to tobacco. This site was selected to evaluate nematicide candidates and compare them to Telone II and Vapam fumigants. The availability and cost of Telone II and new fumigant application regulations have made the use of Telone II less popular to growers. The loss of Temik in 2011 has also reduced the choices growers have to manage their nematode populations. Several candidate nematicides are being evaluated in the vegetable and peanut market, and they were evaluated on tobacco in 2011 at the aforementioned site. The materials evaluated were Telone II, 6 gal/A; Vapam, 37.5 gal/A; Enclosure, 6 qt/A; Temik, 20 lb/A; Mana, 3.31 lb/A, and NEM-EX, 0.75 lb a.i. (0.75 lb + 0.75 lb/A). M. arenaria caused severe damage to tobacco roots, with root knot indices ranging from 1.7 for Telone II to 6.7 for the non-treated control (scale 0-10). Yields for Vapam and Telone II were the highest with yields of 2,860 and 2,641 la/A, respectively. The non-treated plots yielded 1,634 lb/A, while yields for the candidate nematicides were between these extremes. Mana and NEM-EX showed some promise and require further evaluation. (Reprinted with permission)