Field experiments were conducted during the 1991 and 1992 growing seasons to determine suitable varieties and the optimum plant population for flue-cured tobacco ( Nicotiana tabacum L.) grown on bris sandy soil under sprinkler irrigation system. Three flue-cured tobacco varieties (MS 13, MS 26 and MS72) and three plant populations (15.800, 16.600 and 17.500 plants per hectare) were tested. The results showed that there were no variety x plant population interactions with respect to yield and quality. The results also showed that variety MS 26 gave a higher yield and higher nicotine and sugar content in the cured leaf compared to MS 13 and MS 72. The variety MS 72 gave the lowest yield due to high plant mortality. Under the conditions of the two-year study, reducing the plant population from 17.500 to 15.800 plants per hectare increased the cured leaf yield. The grade index and nicotine content were also increased when the plant population was reduced to 15.800 plants per hectare.