Experimental results are presented with three different cigarettes smoked on the same smoking machine at three different altitudes above sea level : +0, +700, +1 300 m. The influence of barometric pressure on the more significant results of smoking and smoke condensate-puff count, crude condensate, nicotine and tar-is analyzed. The combustibility of the cigarette is affected by the barometric pressure in the studied range. This becomes apparent in the puff count values obtained at +700 and +1 300 m which are slightly but significantly higher than the values obtained at sea level. Nevertheless, the analytical results of smoke condensate are not affected by the change in barometric pressure. It is obvious that the lower oxygen partial pressure at higher altitudes has an effect on the mechanisms of cigarette smoke formation, but the final results of TPM, tar and nicotine remains unchanged in the range studied.