CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 16
Loss of heterozygosity analysis of Tk mutants induced by cigarette smoke condensates and their chemical components in L5178Y mouse lymphoma cells
Japan Tobacco Inc., Tobacco Science Research Center, Yokohama, Kanagawa, Japan
For the testing of tobacco smoke genotoxicity in mammalian cells, CORESTA In Vitro Toxicity Testing of Tobacco Smoke Task Force recommends the micronucleus assay (MN), chromosome aberration assay or L5178Y mouse lymphoma assay (MLA). These three...