TSRC, Tob. Sci. Res. Conf., 2022, 75, abstr. 123
Forward dosimetry modeling of cigarette smoke HPHCs in humans using open-source PBPK
ZHANG Jingjie(1); LEE K.M.(2); HINES D.(3); COOK B.(3); BELL S.(3)
(1) Altria Client Services, Glen Allen, VA, USA; (2) Altria Client Services, Richmond, VA, USA; (3) Integrated Laboratory Systems, Morrisville, NC, USA
The levels of harmful and potentially harmful constituents (HPHCs) are often quantitated in cigarettes and emerging smoke-free tobacco products as a proxy for evaluating the potential toxicity of the product. However, the internal dose, such as...