CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, STPOST 50
Vascular endothelial oxidative stress leading to hypertension: development of an AOP using in vitro assays
(1) Ohio Smoking Research Center, Columbus, OH, U.S.A.; (2) British American Tobacco (Investments) Limited, R&D, Southampton, U.K.
Cigarette smoking is associated with diseases including cardiovascular disease. Key events from exposure to cigarette smoke to the development of disease related endpoints can be mapped out in the form of an adverse outcome pathway (AOP). An AOP is a...