TSRC, Tob. Sci. Res. Conf., 2022, 75, abstr. 00 (Symposium) Changes in the tobacco industry: 75 years of TSRC WILLIAMSON F. Global Laboratory Services, Wilson, NC, USA Abstract not available....
TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 058 USP elemental impurities: limit test for metals in nicotine by ICP-MS LOTFI H.; ARROYO M. Global Laboratory Services, Wilson, NC, USA Nicotine included in e-cigarette formulations usually originates as a 90%+ solution, which is purified further prior to use. While the FDA oversees the tobacco industry, there is currently little regulation regarding the quality of raw materials or...
TSRC, Tob. Sci. Res. Conf., 2019, 73, abstr. 107 Predicted impacts of e-cigarettes on us mortality and health care costs POLAND B.(1); LARROQUE S.(2) (1) Certara USA, Menlo Park, CA, USA; (2) JT International, Geneva, Switzerland Introduction: The US FDA seeks to ensure that new tobacco products are appropriate for the protectionof the public health and recommends assessment of tobacco-related morbidity as well as mortality. A simulation model that predicts the effect of...
TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 078 Challenges in the administration of visual analog scales (VAS) during clinical pharmacology trials of ENDS products COPELAND D.; RUSCH L.; FEIN M.; PEARSON M. High Point Clinical Trials Center, High Point, NC, USA Visual Analog Scales (VAS) are an important and commonly used tool for subject feedback in clinical trials. VAS scales subjectively measure characteristics across a range of values which cannot be easily measured by objective techniques or mechanical...
TSRC, Tob. Sci. Res. Conf., 2018, 72, abstr. 109 An improved method for the determination of sodium propionate in tobacco products WILLIAMSON F.; BAILEY J. Global Laboratory Services, Wilson, NC, USA Sodium propionate is a preservative with fungicidal properties that is often added to tobacco, primarily smokeless tobacco products, to prolong shelf life. Several regulatory agencies, including Health Canada and ANVISA, require the testing of sodium...
CORESTA Meeting, Smoke Science/Product Technology, 2017, Kitzbühel, ST 56 Spirometry as an effective tool for screening eligibility in e-cigarette clinical trials PEARSON M.; AUSTIN J.; NUNEZ M.; RUSCH L. High Point Clinical Trials Center, High Point, NC, U.S.A. Emerging claims with regards to electronic cigarette’s usefulness to defer COPD (chronic obstructive pulmonary disease) and other smoking related diseases has launched a wave of clinical research. In the commercial research clinic, spirometry has...
TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 044 Assessing population health effects of tobacco product use for regulatory compliance: a comparison of available methods TEISCHINGER F.(1); POLAND B.(2) (1) JT International, Geneva, Switzerland; (2) Certara USA, Menlo Park, CA, USA The US FDA encourages use of statistical models to project effects of a new tobacco product on population health, for Modified Risk Tobacco Product Applications (MRTPAs) and Pre-Market Tobacco Applications (PMTAs). We review different methods chosen...
TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 105 A clinical site perspective: the use of e-scale versus paper scale to capture subjective measures from tobacco/nicotine withdrawal and product effect questionnaires AUSTIN J.; RUSCH L.; PEARSON M.; NUNEZ M. (presented by Doug Copeland) High Point Clinical Trials Center, High Point, NC, USA Capturing data in an accurate and timely fashion is important in clinical research trials. Visual analog scale (VAS) assessment is often used to evaluate participants' subjective responses to Potential Reduced Exposure Products (PREPs). Advances in...
CORESTA Meeting, Agronomy/Phytopathology, 2015, Izmir, Turkey, AP 32 CPA residue levels in consecutive C48 cases of Oriental tobacco WESTBERG H.; SPENCER A. Global Laboratory Services, Wilson, NC, U.S.A. Crop protection agents (CPA) can be applied to tobacco at various stages of the production cycle and if CPA residues are present in the product, they can be topic of concern. After tobacco is processed it is normally packed into cases or bales for...
TSRC, Tob. Sci. Res. Conf., 2015, 69, abstr. 48 Method development and validation of selected metals in e-liquid samples BROWN J. Global Laboratory Services, Inc., Wilson, NC USA Over the past several years, the use of electronic cigarettes and devices has increased. Analysis of Harmful and Potentially Harmful Constituents is at a forefront in both the conventional and electronic cigarette industries. The analysis of various...