CORESTA Congress, Kunming, 2018, Smoke Science/Product Technology Groups, STPOST 45
Ames assay cytotoxic assessment using bacterial lawn integrity with 35 mm plate spread technique
(1) Enthalpy Analytical, Inc., Henrico, VA, U.S.A.; (2) ToxSynergy LLC, Midlothian, VA, U.S.A.
Background: The Ames assay is commonly used to evaluate the mutagenic potential of tobacco products for regulatory purposes. A significant increase in the number of His+ revertant colonies observed in agar containing Salmonella bacteria and a test...