CORESTA Meeting, Smoke/Technology, Innsbruck, 1999, ST10
LC/MS/MS method for determining NNAL in smokers' urine
R.J. Reynolds Tobacco Company, R&D, Winston-Salem, NC, USA
A sensitive LC/MS/MS method was developed for the determination of two urinary metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) - a tobacco specific nitrosamine. Extraction of the two metabolites,...