TSRC, Tob. Sci. Res. Conf., 2021, 74, abstr. 04 (Symposium) Tobacco harm reduction research and challenges RODU B. University of Louisville, Louisville, KY, USA Abstract not available....
TSRC, Tob. Sci. Res. Conf., 2017, 71, abstr. 057 AKR1C1 as a biomarker for differentiating the biological effects of combustible from non-combustible tobacco products TRAN Q.T.(1); WOO S.(2); HENDERSON D.(2); GAO H.(3); ZACHARIAS W.(3); LIU G.(1); PRASAD G.L.(1) (1) RAI Services Company, Winston-Salem, NC, USA; (2) Axio Research, Seattle, WA, USA; (3) University of Louisville School of Medicine, Louisville, KY, USA Smoking has been established as a major risk factor for developing oral squamous cell carcinoma (OSCC), but less attention has been paid to the effects of smokeless tobacco products. Our objective is to identify potential biomarkers to distinguish...
TSRC, Tob. Sci. Res. Conf., 2012, 66, abstr. 30 Combusted, but not smokeless tobacco product preparations, cause DNA damage in human oral cavity cells ZACHARIAS W.(1); HONG GAO(1); PRASAD G.L.(2) (1) Brown Cancer Center, Univ. of Louisville, Louisville, KY, USA; (2) R.J. Reynolds Tobacco Company, Winston-Salem, NC, USA We examined the effects of reference tobacco preparations on DNA damage in human oral cavity cells. The oral squamous cell carcinoma cell line (101A), normal human gingival epithelial cells (HGEC), and human gingival fibroblasts (HGF) were treated...
CORESTA Congress, Sapporo, 2012, Smoke Science/Product Technology Groups, SSPTPOST 06 Combusted, but not smokeless tobacco product preparations, cause DNA damage in human oral cavity cells ZACHARIAS W.(1); GAO H.(1); PRASAD G.L.(2) (1) Dept. of Medicine, J.G. Brown Cancer Center, University of Louisville, Louisville, KY, USA; (2) R.J. Reynolds Tobacco Co., R&D Department, Winston-Salem, NC, USA We examined the effects of reference tobacco preparations on DNA damage in human oral cavity cells. The oral squamous cell carcinoma cell line (101A), normal human gingival epithelial cells (HGEC), and human gingival fibroblasts (HGF) were treated...
TSRC, Tob. Sci. Res. Conf., 2011, 65, abstr. 30 Microarray-based gene expression profiles of oral cavity cells exposed to different tobacco preparations. ZACHARIAS W.(1); HONG G.(1); PRASAD G.L.(2) (1) Dept. of Medicine, J.G. BROWN Cancer Center, Univ. of Louisville, Louisville, KY; (2) RJ Reynolds Tobacco Co., Winston-Salem, NC, USA Global gene expression profiles were determined for a panel of oral cavity cells in response to treatment by different tobacco preparations. Two human oral squamous cell carcinoma cell lines (101A, 101B) and normal gingival epithelial cells (HGEC)...
Ann. Tabac, 1996, Sect. 1-23, p. 3-14., ISSN.0399-0206 Specific surface area of tobacco from adsorption measurements JADRAQUE D.; RODRIGUEZ MENDIOLA A. Tabacalera S.A., Centro I + D/Embajadores, Madrid, Spain. The specific surface area of two tobacco blends, a dark air-cured and a Virginia, have been measured by the conventional methodology using Kr gas. In an independent set of experiments, the isotherms of water adsorption have been determined for...
CORESTA Meeting, Smoke/Technology, Budapest, 1993, ST 19 A hygrometer gaging method CARDALLIAGUET T.; BARRIO J.C.; SARABIA J. Tabacalera S.A., Centro I + D/Embajadores, Madrid, Spain. The environmental laboratory and conditioning atmosphere are two of the main variables that must be controlled in a laboratory when the cigarette smoke is going to be analyzed. The ISO 3402 rule: Tobacco and Tobacco Products _ Testing and...
Bull. Spec. CORESTA Congress, Jerez de la Frontera, 1992, p. 87, ST13, ISSN.0525-6240 Factor analysis in tobacco characterization JADRAQUE D. Tabacalera S.A., Centro I + D/Embajadores, Madrid, Spain. A factor analysis is applied to the chemical results of about 2,000 samples of different tobaccos from around the world. The chemical analytes considered are the classical of the tobacco, namely, alcaloids, reducing sugars, Kjeldahl N, soluble NH4,...
Bull. Spec. CORESTA Congress, Jerez de la Frontera, 1992, p. 90, ST16, ISSN.0525-6240 An interesting compound of the sidestream smoke of cigarettes : hexamethylenetetraamine SARABIA J.; GONZALEZ J.M. Tabacalera S.A., Centro I + D/Embajadores, Madrid, Spain. Hexamethylenetetraamine-HMTA has been identified in the sidestream smoke condensate of cigarettes. This compound is the result of a well-known reaction between ammonia and formaldehyde. Using the"fish-tail"chimney device for sidestream collection,...
Bull. Spec. CORESTA Congress, Jerez de la Frontera, 1992, p. 98, ST24, ISSN.0525-6240 Rheology in tobacco JADRAQUE D.; PERENA J.M. Tabacalera S.A., Centro I + D/Embajadores, Madrid, Spain. The relationship between mechanical constraints and strain in a material is one of the subjects of rheology. Filling power, shatter index, etc... are important concepts in tobacco. These concepts are technological expressions of the intrinsic...