Search Results

242 results

  1. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 54

    Indoor air chemistry (IAC): comparative study between conventional cigarette and heat-not-burn technology

    GOUJON C.; MAEDER S.
    Philip Morris International R&D, Neuchâtel, Switzerland
    Philip Morris International (PMI) is developing products with the potential to reduce the risk associated with smoking. The Electrically Heated Tobacco System (EHTS) operates by heating a tobacco stick with a holder at a controlled temperature. By heating ...
  2. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, ST 78

    Predictability of in vitro toxicological assessments of cigarettes: analysis of seven years of regulatory submissions to Canadian authorities

    BELUSHKIN M.(1); PIADÉ J-J.(1); CHAPMAN S.(2); FAZEKAS G.(2)
    (1) Philip Morris International R&D, Philip Morris Products S.A., Neuchâtel, Switzerland; (2) Rothmans, Benson & Hedges Inc., Brampton, Ontario, Canada
    Canadian authorities have required the annual submission of a wealth of by-brand information about cigarettes – including analytical data for cut filler and mainstream smoke constituents, for more than a decade. In 2005, the reporting requirements were ...
  3. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, STPOST 21

    Evaluating the genotoxicity of tobacco smoke-derived aerosols using the flow cytometry-based in vitro micronucleus assay

    POULEAU B.; SMART D.J.; McHUGH D.
    Philip Morris International R&D, Philip Morris Products S.A., Neuchâtel, Switzerland
    The in vitro micronucleus (MN) assay is used to assess the genotoxic potential of a test substance by measuring the induction of micronuclei in cultured mammalian cells. The flow cytometry-based assay (in vitro MicroFlow ® kit, Litron Laboratories, USA) ...
  4. CORESTA Congress, Quebec, 2014, Smoke Science/Product Technology Groups, STPOST 23

    Quantitative evaluation of the mutagenicity induced by tobacco smoke-derived total particulate matter using the mouse lymphoma assay

    DEMOUTE A-L.; AL-JOBORI O.; POULEAU B.; SMART D.J.; McHUGH D.
    Philip Morris International R&D, Philip Morris Products S.A., Neuchâtel, Switzerland
    The mouse lymphoma assay (MLA) is a regulatory in vitro test deployed to evaluate the mutagenicity of a test substance via exposure of the thymidine kinase locus in L5178Y mouse lymphoma cells. As part of a proficiency study, we evaluated the mutagenicity ...
  5. CORESTA Meeting, Smoke Science/Product Technology, 2013, Seville, ST 04

    A modified Cambridge filter holder and extraction equipment and methodology to more accurately quantify water in high water content aerosols

    GHOSH D.; JEANNET C.
    Philip Morris International, Research & Development, Neuchâtel, Switzerland
    Philip Morris International is developing products with the potential to reduce the risk of smoking-related diseases by heating tobacco and avoiding combustion. The resulting aerosol has a less complex chemical composition and contains more water than ...
  6. TSRC, Tob. Sci. Res. Conf., 2013, 67, abstr. 84

    Identification of volatiles with nematicidal activities from sphingobacteriumnematocida zy-71-1 and control efficiency to Meloidogyne incognita.

    XI Jiaqin(1); QIN Xijia(1); LIN Dengbin(2); SHENG Yinqi(1); ZHEN Songji(1); HE Moming(3); QUN Xuechao(1); SHAN Wangguang(1); HUA Guojian(1)
    (1) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, P.R.China; (2) Guangxi Tobacco Industrial Co. Ltd, Nanning, P.R. China; (3) Yunnan University, Kunming, P.R. China
    Chemical pesticide is an effective way in controlling tobacco disease, but it caused some problems such as environmental pollution, ecological balance destruction and chemical residues. So biological control of tobacco disease attracts more and more ...
  7. CORESTA Congress, Sapporo, 2012, Agronomy/Phytopathology Groups, APPOST 09

    Cloning and bioinformatic analysis of orange protein (OR) gene from Nicotiana tabacum

    LEI Bo(1); LU Kun(2); DING Fu-zhang(1); LIU Xiao-rong(2); HU Zhong-yi(1); PAN Wen-jie(1)
    (1) Guizhou Tobacco Science Research Institute, Guiyang, Guizhou, P.R. China; (2) College of Agronomy and Biothehnology of Southwest University, Chongqing, P.R. China
    Previous microarray results indicated that the orange protein (OR) gene in the carotenoid biosynthesis pathway showed significant differential expression in leaves between moderate and light aroma tobacco areas. In order to obtain the full-length sequence ...
  8. CORESTA Congress, Sapporo, 2012, Agronomy/Phytopathology Groups, APPOST 12

    Biocontrol efficiencies and identification of nematicidal metabolite from strain BJLSH9 towards nematode and Phytophthora nicotianae

    DUAN Yan-qing(1); LI Ping(2); ZHE Wei(1); XI Jia-qin(3); XIA Jianjun(1); WANG Wenyuan(1); JIANG Junxiang(1); MO Ming-he(2)
    (1) Technology Center of Hongyun Honghe Tobacco (Group) Co., Ltd, Wuhua District, Kunming, P.R. China; (2) Key Laboratory for Conservation and Utilisation of Bio-Resources, Yunnan University, Kunming, P.R. China; (3) Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, P.R. China
    BJLSH9, an actinomycete exhibiting both nematicidal and antifungal activities, was isolated from rhizospheric soil of willow in Beijing. Bioassay results in vivo showed that BJLSH9 displayed a 50.05% efficiency to suppress radial growth of Phytophthora ...
  9. CORESTA Congress, Sapporo, 2012, Plenary Session, abstr. IG 02

    Levels of tobacco-specific N-nitrosamines NNN and NNK in commercial cigarettes sampled in2008-2010 – A review of analytical data

    GUNDUZ I.(1); KONDYLIS A.(1); HOFER R.(1); JACCARD G.(2); RUFFIEUX L.(3); GADANI F.(1)
    (1) Philip Morris Products SA, Product Development – Applied Cigarette Research, Neuchatel, Switzerland; (2) Philip Morris International Management SA, Product and Process Quality, Neuchatel, Switzerland; (3) Philip Morris International Management SA, Agricultural Programs, Lausanne, Switzerland
    The present study was designed to determine levels of the tobacco-specific N-nitrosamines (TSNAs) N’-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in tobacco cut filler and in mainstream smoke of commercial cigarette ...